Published in Rheumatology International (Sep 2014) Authors: Bjersing J et al Fibromyalgia (FM) is characterized by generalized chronic pain and reduced pain thresholds. Disturbed neuroendocrine function and impairment of growth hormone/insulin-like growth factor-1 is common. However, the pathophysiology of FM is not clear. MicroRNAs are important regulatory factors reflecting interface of genes and environment. Our […]
Read MoreMemantine, a drug primarily used to treat patients with Parkinson’s disease and Alzheimer’s disease, reduced pain and improved quality of life in patients with fibromyalgia, according to a study published in Pain. “This is the first randomised, controlled study of memantine for the treatment of fibromyalgia,” write Bárbara Oliván-Blázquez, from the Department of Psychology and […]
Read MorePatients who receive epinephrine during resuscitation after cardiac arrest are less likely to survive with a good neurologic outcome, a study in the Journal of the American College of Cardiology suggests. Researchers analyzed data from more than 1500 patients who were successfully resuscitated after an out-of-hospital cardiac arrest and were subsequently treated at a large […]
Read MoreAuthors: Cohen SP et al., Anesthesiology 2014 Nov 121:1045 In a nonblinded, randomized trial, epidural steroid injections were not significantly better than conservative treatment. Data on epidural steroid injections for cervical radiculopathy are largely observational, and results of the few small randomized trials have been inconclusive. In this multicenter trial, U.S. investigators randomized 169 patients […]
Read MorePublished in Pediatr Blood Cancer. 2015 Jan;62(1):85-90. Authors: Whitlow PG et al BACKGROUND: Lumbar punctures are frequently performed in pediatric leukemia for central nervous system leukemic prophylaxis. The contribution of local anesthetic with deep sedation is unknown. The objective was to evaluate EMLA (eutectic mixture of local anesthetics) cream as a pain reliever in conjunction […]
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