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Uncategorized Published - 17 March, 2015    By - Dr Clemens
Rocuronium Blockade Reversal With Sugammadex vs. Neostigmine

Randomized Study in Chinese and Caucasian Subjects Authors: Xinmin Wu et al Published in BMC Anesthesiol. 2014;14(53) Background This study compared efficacy and safety of the selective relaxant binding agent sugammadex (2 mg/kg) with neostigmine (50 μg/kg) for neuromuscular blockade (NMB) reversal in Chinese and Caucasian subjects. Methods This was a randomized, active-controlled, multicenter, safety-assessor-blinded study (NCT00825812) in […]

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Uncategorized Published - 17 March, 2015    By - Dr Clemens
Comparison of pain outcomes between two anti-GD2 antibodies in patients with neuroblastoma

Article of our pain providers. Published in Pediatr Blood Cancer © 2014 Wiley Periodicals, Inc. Author(s): Anghelescu D, Goldberg J, Faughnan L, Wu J, Mao S, Furman W, Santana V, Navid F Treatments discussed: ch14.18, morphine BACKGROUND Addition of anti-GD2 antibody ch14.18 to the treatment of neuroblastoma has improved outcomes. The most common side effect of ch14.18 […]

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Uncategorized Published - 17 March, 2015    By - Dr Clemens
Symptom Burden Best Predictor of Concussion Recovery

This is for our pain clinic providers. The best predictor of a speedy recovery after a sports-related concussion is simply the initial symptom burden as measured by the Post-Concussion Symptom Scale (PCSS), a new study suggests. Other measures, including computerized neurocognitive testing, are not predictive, according to the study results. “The bottom line is that […]

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Uncategorized Published - 17 March, 2015    By - Dr Clemens
Legally Prescribed Opioid Use May Increase Mortality in Patients With Chronic Pain

A study published in the November issue of the journal Pain found an increased risk of death associated with chronic pain without opioid treatment, as well as an even higher risk among those prescribed opioids for long-term use and a somewhat lower risk associated with short-term use. “Our study provides the first evidence that directly […]

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Uncategorized Published - 16 March, 2015    By - Dr Clemens
Lower-Dose Diclofenac Improves Pain in Osteoarthritis

This is for our providers treating chronic pain patients. For patients with osteoarthritis, a formulation of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac, developed with SoluMatrix fine-particle technology (Zorvolex, Iroko Pharmaceuticals), improves health-related quality of life, physical function, and pain, according to a phase 3 open-label study. “We re-engineered diclofenac to enable lower doses to be used, […]

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