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Uncategorized Published - 17 February, 2015    By - Dr Clemens
Do Abdominal Pain and Tenderness Predict Injury in Children with Blunt Abdominal Trauma?

Published in J Pediatr 2014 Dec 165:1230 Authors: Adelgais KM et al. Abdominal tenderness, more than abdominal pain, predicted intra-abdominal injury and need for acute intervention. To evaluate the accuracy of patient-reported abdominal pain and physician-assessed abdominal tenderness for predicting intra-abdominal injuries in children, investigators conducted a planned secondary analysis of patients <18 years of […]

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Uncategorized Published - 17 February, 2015    By - Dr Clemens
Efforts Needed to Curb Opioid Prescriptions Among Reproductive-Aged Women

Opioids are frequently prescribed to reproductive-aged women in the U.S., raising concerns about fetal exposure in unrecognized or unintended pregnancies, an MMWR article finds. Opioid exposure during pregnancy is potentially associated with increased risks for neonatal abstinence syndrome and birth defects. CDC researchers examined two databases — one of Medicaid recipients and the other of […]

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Uncategorized Published - 17 February, 2015    By - Dr Clemens
Transfusion Threshold for Abdominal Cancer Surgery Patients

Published in Anesthesiology 2015 Jan 122:29 Authors: Pinheiro de Almeida J et al. A hemoglobin level of 9 g/dL was superior to 7 g/dL as a trigger for transfusion. Randomized trials have shown favorable outcomes with a restrictive red-cell transfusion strategy — that is, not transfusing until hemoglobin levels are <7 g/dL in general critical-care […]

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Uncategorized Published - 16 February, 2015    By - Dr Clemens
Ketorolac Tromethamine Injection by Hospira: Recall – Particulate in Glass Vials

Food and Drug Administration (US) AUDIENCE: Pharmacy, Case Manager ISSUE: Hospira announced a voluntary recall of ketorolac tromethamine injection, USP in the United States and Singapore due to potential particulate. The presence of particulate has been confirmed through a customer report of visible, floating particulate identified in glass fliptop vials. The particulate was identified as […]

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Uncategorized Published - 16 February, 2015    By - Dr Clemens
Structural Comparisons of Ligand-gated Ion Channels in Open, Closed, and Desensitized States Identify a Novel Propofol-binding Site on Mammalian γ-Aminobutyric Acid Type A Receptors

Published in The Journal of the American Society of Anesthesiologists on 1 2015. Authors: Nicholas P. Franks, F.R.C.A., F.Med.Sci., F.R.S. Background: Most anesthetics, particularly intravenous agents such as propofol and etomidate, enhance the actions of the neurotransmitter γ-aminobutyric acid (GABA) at the GABA type A receptor. However, there is no agreement as where anesthetics bind […]

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