Authors: Andrea Rossetto, M.D. et al  Anesthesiology November 2021. Background The relationship between late clinical outcomes after injury and early dynamic changes between fibrinolytic states is not fully understood. The authors hypothesized that temporal transitions in fibrinolysis states using rotational thromboelastometry (ROTEM) would aid stratification of adverse late clinical outcomes and improve understanding of how […]

Authors: Philip M. Hartigan, M.D. et al  Anesthesiology November 2021. Background Central airway occlusion is a feared complication of general anesthesia in patients with mediastinal masses. Maintenance of spontaneous ventilation and avoiding neuromuscular blockade are recommended to reduce this risk. Physiologic arguments supporting these recommendations are controversial and direct evidence is lacking. The authors hypothesized […]

DG News The use of acetaminophen before surgery for rotator cuff repair resulted in better pain control and a decline in opioid use, according to a study published in the Journal of Shoulder and Elbow Surgery. The prospective, randomised, 3-arm study compared the impact of oxycodone 5 mg every 6 hours as needed plus oral […]

DG News Extended opioid usage occurred in older patients, aged 60 years and up, who undergo fracture surgery, according to a study presented at the 2021 Virtual Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). Investigators looked at 29,618 patients who were naïve to opioids and underwent hip fracture surgery between 2009 and […]

Author: Beth Sissons MedicalNewsToday Migraine prophylaxis, or prevention treatment, may help reduce or prevent migraine attacks. Prophylaxis may include medication, integrative therapies such as acupuncture and behavioral therapy, or a combination of both. Migraine prophylaxis may help reduce the frequency of migraine headaches, decrease pain intensity, and improve quality of life. Evidence suggests there are effective […]

We want to thank all of our readers a Happy Thanksgiving.  Please be safe and don’t overeat.

Authors: Christian Reiterer, M.D. et al  Anesthesiology November 2021. Background Colloids are thought to sustain blood pressure and cardiac index better than crystalloids. However, the relative effects of intraoperative hydroxyethyl starch and crystalloid administration on the cardiac index and blood pressure remain unclear. This study therefore tested in this subanalysis of a previously published large […]

Authors: Chris A. Rishel, M.D., Ph.D. et al  Anesthesiology December 2021, Vol. 135, 1015–1026. Background Among chronic opioid users, the association between decreasing or increasing preoperative opioid utilization and postoperative outcomes is unknown. The authors hypothesized that decreasing utilization would be associated with improved outcomes and increasing utilization with worsened outcomes. Methods Using commercial insurance […]

Authors: Moritz Kretzschmar, M.D., Ph.D., D.E.S.A. et al  Anesthesiology December 2021, Vol. 135, 1027–1041. Background Previous studies have established the role of various tissue compartments in the kinetics of inhaled anesthetic uptake and elimination. The role of normal lungs in inhaled anesthetic kinetics is less understood. In juvenile pigs with normal lungs, the authors measured […]

This is for our readers that treat pain patients. Author: Louise Gagnon DG News Injecting onabotulinumtoxinA into pelvic floor muscles with spasms provided pain relief in women with endometriosis-related chronic pain refractory to standard treatment, according to a study presented at the 2021 Annual Meeting of the American Society for Reproductive Medicine (ASRM). “We chose […]