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Study finds fentanyl transdermal patches are too often prescribed to opioid-naïve and elderly patients, raising their risks of fatal adverse drug events. Interview with Caleb Alexander, MD Fentanyl patches are a highly potent options for cancer and non-cancer pain patients, but are contraindicated in opioid naïve patients. However, new research indicates that physicians may be […]
Read MoreAuthors: Andrew P. Wojtovich, Ph.D. et al Anesthesiology 5 2016, Vol.124, 1065-1076. Background: Anesthetic preconditioning (APC) is a clinically important phenomenon in which volatile anesthetics (VAs) protect tissues such as heart against ischemic injury. The mechanism of APC is thought to involve K+ channels encoded by the Slo gene family, and the authors showed previously that slo-2 is required for APC inCaenorhabditis […]
Read MoreEdited by Susan Sadoughi, MD, and André Sofair, MD, MPH Contrary to its marketing claims, OxyContin’s pain-relieving effects often fall short of 12 hours in many patients, which can lead to a host of other problems, according to an investigation by the Los Angeles Times. OxyContin is approved for 12-hour dosing. Several studies found that the drug’s effects […]
Read MoreAuthors: Roy G. Soto, M.D. et al ASA Monitor 05 2016, Vol.80, 28-29. First off, let’s agree on two basic concepts: capitalism is good and patient safety is good. For decades we have been tempted with a never-ending parade of new, expensive devices and medications that are touted to improve safety and outcomes. Sometimes the acquisition cost […]
Read MoreAuthors: Matthew E. Patterson, M.D. et al ASA Monitor 05 2016, Vol.80, 26-27. The Perioperative Surgical Home (PSH) model of care has been developed in an attempt to streamline patient recovery by providing evidence-based care and reducing care variability. Although much attention has been placed on medications, techniques and devices that can accomplish this variability reduction, we […]
Read MoreAuthors: Keith J. Ruskin, M.D. et al ASA Monitor 05 2016, Vol.80, 20-21. Every industry has taken steps to improve employee safety by decreasing the possibility of industrial accidents and individual injuries. Mass transportation and health care are significantly different from other business sectors (e.g., manufacturing) and share several common features. For example, a factory might […]
Read MoreAuthors: Antoine Monsel, M.D., M.Sc. et al Anesthesiology 5 2016, Vol.124, 1041-1052. Background: Patients undergoing major vascular surgery often develop postoperative pneumonia that impacts their outcomes. Conflicting data exist concerning the potential benefit of tapered-shaped cuffs on tracheal sealing. The primary objective of this study was to assess the efficiency of a polyvinyl chloride tapered-cuff endotracheal tube […]
Read MoreAuthors: Davinder Ramsingh, M.D. et al Anesthesiology 5 2016, Vol.124, 1012-1020 Background: Unrecognized malposition of the endotracheal tube (ETT) can lead to severe complications in patients under general anesthesia. The focus of this double-blinded randomized study was to assess the accuracy of point-of-care ultrasound in verifying the correct position of the ETT and to compare it with […]
Read MoreA new survey shows that almost 70% of headache specialists report having episodic migraine (EM), much higher than the lifetime incidence of EM in the general population. Overall, only about 30% of respondents said they have no personal history of any of seven possible headache types. The survey also showed that many clinicians prefer treating […]
Read MoreAuthors: Jeff Simmons, M.D. et al ASA Monitor 05 2016, Vol.80, 16-18. Scenario: You have just performed the most altruistic act in the practice of anesthesia: giving a lunch break to someone in the GI lab. Of course, the ERCP is just getting started and the morbidly obese patient has just been positioned prone. He is […]
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