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Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 626–633 AUTHORS: Applegate, Richard L. II MD et al BACKGROUND: The use of intraoperative pulse oximetry (SpO2) enhances hypoxia detection and is associated with fewer perioperative hypoxic events. However, SpO2 may be reported as 98% when arterial partial pressure of oxygen (PaO2) is […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 610–615 AUTHORS: Langford, Roger A. BMBS, FRCA et al BACKGROUND: We compared plasma and cerebrospinal fluid (CSF) pharmacokinetics of paracetamol after intravenous (IV) and oral administration to determine dosing regimens that optimize CSF concentrations. METHODS: Twenty-one adult patients were assigned randomly to […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 597–606 AUTHORS: Qiu, Chunyuan MD, MS et al BACKGROUND: In this article, we report on the implementation and impact of a Perioperative Surgical Home (PSH) model for the total knee arthroplasty at an integrated delivery system (Kaiser Permanente). METHODS: A multidisciplinary committee […]
Read MoreFor the antifibrinolytic agent tranexamic acid, doses varying between 5 and 15 mg/kg failed to produce a dose-dependent drop in hemoglobin after total knee (TKA) or total hip arthroplasty (THA), leading study investigators to recommend using the lowest of these doses in orthopedic patients. “At my institution, we reviewed quite a bit of data while […]
Read MoreContinuing a series begun last year, we asked D. John Doyle, MD, PhD, a member of the Anesthesiology News advisory board, to pose 7 questions to an international airway management roundtable, whose members he picked. The responses, including those of Dr Doyle, follow. John Doyle, MD, PhD Chief of General Anesthesiology Anesthesiology Institute Cleveland Clinic […]
Read MoreWith a new push to combat the opioid abuse epidemic, the Substance Abuse and Mental Health Services Administration (SAMHSA) has launched a new smartphone app providing essential resources for health care providers. The recent push to get more patients access to medication assisted treatment (MAT) for opioid addiction, and more doctors trained to provide it, […]
Read MoreThree months of osteopathic manipulative treatment has been shown to be effective for chronic low back pain, with improved results lasting up to 1 year. By Leonard B. Goldstein, DDS, PhD, Victoria A. Troncoso, DO, Deborah Heath, DO, Katrina Wilson, OMS-IV and Roya Vahdatinia, OSM-IV Low back pain (LBP) is one of the most prevalent […]
Read MoreRates of the primary outcome — a 50% or greater relative reduction in the number of headache days — were similar in the amitriptyline, topiramate, and placebo groups (52%, 55%, and 61%). The groups also did not differ significantly in the change in headache-related disability, change in number of headache days, or incidence of serious […]
Read MoreStacie Deiner, M.D., M.S.: ‘One of the things we anesthesiologists might not do as well as we should is give a drug and wait for it to work. There is a benefit in that for the elderly.’ There is a “silver tsunami” of growing evidence that anesthesia could pose a greater risk of cognitive side […]
Read MoreBy Thomas G. Ciccone Interview with Peter Pryzbylkowski, MD Platelet-rich plasma (PRP) is a therapy in which doctors inject patients with a highly concentrated plasma solution in order to promote natural healing of damaged tissue. Although its first use dates back to the 1950s, PRP’s growing popularity in recent years has led to a serious assessment of […]
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