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Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 758–761 AUTHORS: Gabriel, Rodney A. MD et al The interscalene block (ISB) is a common adjunct to general anesthesia for total shoulder arthroplasty (TSA). The aim of the study was to report the current national demographics of the patients who are receiving […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 749–757 AUTHORS: Turan, Alparslan MD et al BACKGROUND: Clonidine is an α2-adrenoceptor agonist, which has analgesic properties. However, the analgesic efficacy of perioperative clonidine remains unclear. We, therefore, tested the hypothesis that clonidine reduces both pain scores and cumulative opioid consumption during […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 684–689 AUTHORS: Zaphiratos, Valerie MD, MSc BACKGROUND: Combined spinal-epidural (CSE) analgesia is widely used for delivering labor analgesia. Epidural volume extension (EVE) involves the injection of fluid into the epidural space compressing the dural sac, causing cephalad shift of the cerebral spinal […]
Read MoreClark W et al. Lancet 2016 Aug 17. Hirsch JA and Chandra RV. Lancet 2016 Aug 17. The procedure benefitted some highly selected patients when performed a few weeks after vertebral fracture. Vertebroplasty is injection of polymethylmethacrylate “cement” into a fractured vertebral body to reduce pain and disability. The popularity of this procedure declined after 2009, when two randomized, sham-controlled […]
Read MoreResearchers have determined that patients who have not had an opioid prescription within 1 year prior to their procedure are at low risk of developing persistent opioid use after major surgery. The research, published online by JAMA Surgery, showed that of the 39,140 observed patients only 0.4% (~1 in every 225 patients) continued to receive ongoing […]
Read MoreUsing the common pain-relieving medication acetaminophen during pregnancy was associated with increased risk for multiple behavioural problems in children, according to an article published online by JAMA Pediatrics. Acetaminophen is generally considered safe in pregnancy and is used by a many pregnant women for pain and fever. Evie Stergiakouli, PhD, University of Bristol, Bristol, United […]
Read MoreArthur L. Caplan, PhD Hi. I’m Art Caplan from the Division of Medical Ethics and the New York University (NYU) Langone Medical Center. A former student of mine, who is now in medical school, asked me a question that comes up again and again. I have not talked about it here, but I think it […]
Read MoreScientists are testing an experimental drug that’s designed to have the painkilling power of morphine without some of the side effects that can lead to overdose deaths. Initial results in mice with the compound known for now as PZM21 suggest it might be less addictive than morphine and other opiate painkillers and avoid respiratory depression […]
Read MoreAuthors: Hitoshi Sato et al BMC Anesthesiol. 2016;16(47) Background: Compared to conventional tidal volume ventilation, low tidal-volume ventilation reduces mortality in cased of acute respiratory distress syndrome. The aim of the present study is to determine whether low tidal-volume ventilation reduces the production of inflammatory mediators in the lungs and improves physiological status during hepatic […]
Read MoreLearn more about the use of subanesthetic dosages of IV agents in an outpatient headache and chronic pain clinic. By John Claude Krusz, PhD, MD Most pain practitioners now believe that neuroinflammation plays a role in the initiation, maintenance, and exacerbation of the chronic pain process in the nervous system—both centrally and peripherally.1 Microglial cell activation in […]
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