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Uncategorized Published - 21 May, 2021    By - Dr Clemens
Association Between Cerebral Desaturation and Postoperative Delirium in Thoracotomy With One-Lung Ventilation

AUTHORS: Cui, Fan MD et al Anesthesia & Analgesia: March 15, 2021 BACKGROUND: The association between cerebral desaturation and postoperative delirium in thoracotomy with one-lung ventilation (OLV) has not been specifically studied. METHODS: A prospective observational study performed in thoracic surgical patients. Cerebral tissue oxygen saturation (Scto2) was monitored on the left and right foreheads using […]

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Uncategorized Published - 21 May, 2021    By - Dr Clemens
Unanticipated Consequences of Switching to Sugammadex

AUTHORS: Dwan, Robyn L. DO et al Anesthesia & Analgesia: March 8, 2021 BACKGROUND: Sugammadex binds progesterone with high affinity and may interfere with hormonal contraceptive effectiveness. The clinical, economical, and ethical implications of unintended pregnancy should prompt anesthesiologists to actively consider and manage this pharmacologic interaction. We surveyed anesthesiology providers at our institution about knowledge […]

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Uncategorized Published - 21 May, 2021    By - Dr Clemens
Postoperative Hypotension and Adverse Clinical Outcomes in Patients Without Intraoperative Hypotension, After Noncardiac Surgery

AUTHORS: Khanna, Ashish K. MD, FCCP, FCCM et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1410-1420 BACKGROUND:  Postoperative hypotension (POH) is associated with major adverse events. However, little is known about the association of blood pressure thresholds and outcomes in postoperative patients without intraoperative hypotension (IOH) on the general-care […]

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Uncategorized Published - 21 May, 2021    By - Dr Clemens
Non-Invasive Respiratory Support for Management of the Perioperative Patient

DG Journal Club AUTHORS: Sharon Einav, Ines Lakbar et al. Adv Ther. 2021 Mar 6 BACKGROUND Non-invasive respiratory support including high-flow nasal oxygen (HFNO), continuous positive airway pressure (CPAP) or bilevel positive airway pressure (BiPAP) is routinely used in the perioperative period. OBJECTIVES The aim of this narrative review was to discuss some of the […]

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Uncategorized Published - 21 May, 2021    By - Dr Clemens
Influence of Different Measurements on the Ability of P-SAP and DES-OSA Scores to Detect Severe Obstructive Sleep Apnea

AUTHORS: Deflandre, Eric P. MD, PhD, FCCP, FAHA et al Anesthesia & Analgesia: March 15, 2021 BACKGROUND: Severe obstructive sleep apnea (sOSA) represents a risk factor of postoperative complications. Perioperative sleep apnea prediction (P-SAP) and DES-obstructive sleep apnea (DES-OSA) (DES being the acronym for 2 of the participating investigators and OSA for obstructive sleep apnea) scores […]

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Uncategorized Published - 20 May, 2021    By - Dr Clemens
Association of Obstructive Sleep Apnea With Difficult Intubation

AUTHORS: Seet, Edwin MMed et al Anesthesia & Analgesia: March 10, 2021 BACKGROUND: Obstructive sleep apnea (OSA) has been found to be associated with difficult airway, although there is a paucity of prospective studies investigating thresholds of OSA severity with difficult airway outcomes. The aim of this study was to examine the association between OSA and […]

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Uncategorized Published - 20 May, 2021    By - Dr Clemens
Prevention of Cardiac Surgery–Associated Acute Kidney Injury by Implementing the KDIGO Guidelines in High-Risk Patients Identified by Biomarkers

AUTHORS: Zarbock, Alexander MD et al Anesthesia & Analgesia: March 8, 2021 BACKGROUND: Prospective, single-center trials have shown that the implementation of the Kidney Disease: Improving Global Outcomes (KDIGO) recommendations in high-risk patients significantly reduced the development of acute kidney injury (AKI) after surgery. We sought to evaluate the feasibility of implementing a bundle of supportive […]

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Uncategorized Published - 20 May, 2021    By - Dr Clemens
Effects of preoperative Carbamazepine treatment on Microvascular Decompression for Classical Trigeminal Neuralgia

DG Journal Club AUTHORS: Dixiang Song, Jianguo Li et al. World Neurosurg. 2021 Feb 26 BACKGROUND Carbamazepine (CBZ) is the first-line therapy for Trigeminal Neuralgia (TGN), and Microvascular Decompression (MVD) is considered as an effective surgical treatment for TGN. But the effect of preoperative CBZ treatment for MVD outcome is not clear. METHODS A total […]

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Uncategorized Published - 20 May, 2021    By - Dr Clemens
Epidural analgesia during labor and its optimal initiation time-points: A real-world study on 400 Chinese nulliparas

DG Journal Club AUTHORS: Ying Zha, Xun Gong et al. Medicine (Baltimore). 2021 Mar 5; 100(9): e24923 ABSTRACT Recent research has suggested that 6 cm of cervical dilation should be the threshold for the active labor phase, and it has confirmed that epidural analgesia (EA) is a safe method of pain relief during labor. However, the […]

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Uncategorized Published - 20 May, 2021    By - Dr Clemens
Timeline of pain before dementia diagnosis: a 27-year follow-up study

DG Journal Club Authors: Sushmithadev Kumaradev, Aurore Fayosse et al. Pain. 2021 May 1; 162(5): 1578-1585 ABSTRACT This study examines the importance of length of follow-up on the association between pain and incident dementia. Further objective was to characterize pain trajectories in the 27 years preceding dementia diagnosis and compare them with those among persons […]

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