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Uncategorized Published - 20 May, 2021    By - Dr Clemens
Effects of preoperative Carbamazepine treatment on Microvascular Decompression for Classical Trigeminal Neuralgia

DG Journal Club AUTHORS: Dixiang Song, Jianguo Li et al. World Neurosurg. 2021 Feb 26 BACKGROUND Carbamazepine (CBZ) is the first-line therapy for Trigeminal Neuralgia (TGN), and Microvascular Decompression (MVD) is considered as an effective surgical treatment for TGN. But the effect of preoperative CBZ treatment for MVD outcome is not clear. METHODS A total […]

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Uncategorized Published - 20 May, 2021    By - Dr Clemens
Epidural analgesia during labor and its optimal initiation time-points: A real-world study on 400 Chinese nulliparas

DG Journal Club AUTHORS: Ying Zha, Xun Gong et al. Medicine (Baltimore). 2021 Mar 5; 100(9): e24923 ABSTRACT Recent research has suggested that 6 cm of cervical dilation should be the threshold for the active labor phase, and it has confirmed that epidural analgesia (EA) is a safe method of pain relief during labor. However, the […]

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Uncategorized Published - 20 May, 2021    By - Dr Clemens
Timeline of pain before dementia diagnosis: a 27-year follow-up study

DG Journal Club Authors: Sushmithadev Kumaradev, Aurore Fayosse et al. Pain. 2021 May 1; 162(5): 1578-1585 ABSTRACT This study examines the importance of length of follow-up on the association between pain and incident dementia. Further objective was to characterize pain trajectories in the 27 years preceding dementia diagnosis and compare them with those among persons […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Perioperative Ulnar Neuropathy: A Contemporary Estimate of Incidence and Risk Factors

AUTHORS: Pulos, Bridget P. MD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1429-1437 BACKGROUND:  Retrospective and prospective studies 2 decades ago from the authors’ institution reported the incidence of perioperative ulnar neuropathy persisting for at least several months in a noncardiac adult surgical population to be between 30 […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Anesthesia for children with complete trisomy 18 (Edwards syndrome)

DG Journal Club AUTHORS: Erin E Birmingham, Astrid G Stucke et al. Paediatr Anaesth. 2021 Feb 28 BACKGROUND Trisomy 18 or Edwards syndrome is the second most common aneuploidy with a prevalence between 1/3000 and 1/10 000 live births. The syndrome encompasses malformations of the central nervous, cardiac, respiratory, gastrointestinal, and genitourinary systems. Trisomy 18 carries […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Evaluation of Drug Wastage in the Operating Rooms and Intensive Care Units of a Regional Health Service

AUTHORS: Barbariol, Federico MD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1450-1456 BACKGROUND:  Pharmacological treatments for critical processes in patients need to be initiated as rapidly as possible; for this reason, it is a standard of care to prepare the main anesthesia and emergency drugs in advance. As […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Systematic review of outcomes and endpoints in acute migraine clinical trials

DG Journal Club AUTHORS: Carrie R Houts, James S McGinley et al. Headache. 2021 Feb; 61(2): 263-275 BACKGROUND/OBJECTIVE To review the acute migraine clinical trial literature and provide a summary of the endpoints and outcomes used in such trials. METHOD A systematic literature review, following a prespecified (but unregistered) protocol developed to adhere to recommendations […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Dimethyl Fumarate Reduces Oxidative Stress and Pronociceptive Immune Responses in a Murine Model of Complex Regional Pain Syndrome

AUTHORS: Guo, Tian-Zhi MD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1475-1485 BACKGROUND:  Complex regional pain syndrome (CRPS) is a highly disabling cause of pain often precipitated by surgery or trauma to a limb. Both innate and adaptive immunological changes contribute to this syndrome. Dimethyl fumarate (DMF) works […]

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Uncategorized Published - 18 May, 2021    By - Dr Clemens
Subcostal Anterior Quadratus Lumborum Block Versus Epidural Block for Analgesia in Open Nephrectomy

AUTHORS: Elsharkawy, Hesham MD, MBA, MSc, FASA et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 1138-1145 BACKGROUND:  Epidural block are often used for analgesia after open nephrectomy surgery. Subcostal anterior quadratus lumborum block may be an alternative. We therefore tested the hypothesis that the continuous subcostal anterior quadratus lumborum […]

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Uncategorized Published - 18 May, 2021    By - Dr Clemens
Availability of Inpatient Pediatric Surgery in the United States

Authors: Michael L. McManus, M.D., M.P.H. et al Anesthesiology June 2021, Vol. 134, 852–861. Background In 2015, the American College of Surgeons began its Children’s Surgery Verification Quality Improvement Program, promulgating standards intended to promote regionalization and improve pediatric surgical care. It was hypothesized that pediatric surgical care was already highly regionalized and concentrated before […]

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