Authors: Alexander J. Butwick, M.B.B.S., F.R.C.A., M.S. et al Anesthesiology June 2021, Vol. 134, 874–886. Background Risk factors for postpartum hemorrhage, such as chorioamnionitis and multiple gestation, have been identified in previous epidemiologic studies. However, existing data describing the association between gestational age at delivery and postpartum hemorrhage are conflicting. The aim of this study was […]
Read MoreAuthors: Gen Li, M.Stat et al Anesthesiology June 2021, Vol. 134, 862–873. Background Postoperative residual neuromuscular blockade related to nondepolarizing neuromuscular blocking agents may be associated with pulmonary complications. In this study, the authors sought to determine whether sugammadex was associated with a lower risk of postoperative pulmonary complications in comparison with neostigmine. Methods Adult patients […]
Read MoreAUTHORS: Macias, Paul MD, MS, RD et al Anesthesia & Analgesia: March 15, 2021 BACKGROUND: Pregnancy-related cardiovascular physiologic changes increase the likelihood of pulmonary edema, with the risk of fluid extravasating into the pulmonary interstitium being potentially at a maximum during the early postpartum period. Data on the impact of labor and peripartum hemodynamic strain on […]
Read MoreAUTHORS: Cui, Fan MD et al Anesthesia & Analgesia: March 15, 2021 BACKGROUND: The association between cerebral desaturation and postoperative delirium in thoracotomy with one-lung ventilation (OLV) has not been specifically studied. METHODS: A prospective observational study performed in thoracic surgical patients. Cerebral tissue oxygen saturation (Scto2) was monitored on the left and right foreheads using […]
Read MoreAUTHORS: Dwan, Robyn L. DO et al Anesthesia & Analgesia: March 8, 2021 BACKGROUND: Sugammadex binds progesterone with high affinity and may interfere with hormonal contraceptive effectiveness. The clinical, economical, and ethical implications of unintended pregnancy should prompt anesthesiologists to actively consider and manage this pharmacologic interaction. We surveyed anesthesiology providers at our institution about knowledge […]
Read MoreAUTHORS: Khanna, Ashish K. MD, FCCP, FCCM et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1410-1420 BACKGROUND: Postoperative hypotension (POH) is associated with major adverse events. However, little is known about the association of blood pressure thresholds and outcomes in postoperative patients without intraoperative hypotension (IOH) on the general-care […]
Read MoreDG Journal Club AUTHORS: Sharon Einav, Ines Lakbar et al. Adv Ther. 2021 Mar 6 BACKGROUND Non-invasive respiratory support including high-flow nasal oxygen (HFNO), continuous positive airway pressure (CPAP) or bilevel positive airway pressure (BiPAP) is routinely used in the perioperative period. OBJECTIVES The aim of this narrative review was to discuss some of the […]
Read MoreAUTHORS: Deflandre, Eric P. MD, PhD, FCCP, FAHA et al Anesthesia & Analgesia: March 15, 2021 BACKGROUND: Severe obstructive sleep apnea (sOSA) represents a risk factor of postoperative complications. Perioperative sleep apnea prediction (P-SAP) and DES-obstructive sleep apnea (DES-OSA) (DES being the acronym for 2 of the participating investigators and OSA for obstructive sleep apnea) scores […]
Read MoreAUTHORS: Seet, Edwin MMed et al Anesthesia & Analgesia: March 10, 2021 BACKGROUND: Obstructive sleep apnea (OSA) has been found to be associated with difficult airway, although there is a paucity of prospective studies investigating thresholds of OSA severity with difficult airway outcomes. The aim of this study was to examine the association between OSA and […]
Read MoreAUTHORS: Zarbock, Alexander MD et al Anesthesia & Analgesia: March 8, 2021 BACKGROUND: Prospective, single-center trials have shown that the implementation of the Kidney Disease: Improving Global Outcomes (KDIGO) recommendations in high-risk patients significantly reduced the development of acute kidney injury (AKI) after surgery. We sought to evaluate the feasibility of implementing a bundle of supportive […]
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