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Uncategorized Published - 25 May, 2021    By - Dr Clemens
Comparison between epidural and intravenous analgesia effects on disease-free survival after colorectal cancer surgery

DG Journal Club Wiebke Falk, Anders Magnuson et al. Br J Anaesth. 2021 May BACKGROUND Thoracic epidural analgesia (TEA) has been suggested to improve survival after curative surgery for colorectal cancer compared with systemic opioid analgesia. The evidence, exclusively based on retrospective studies, is contradictory. METHODS In this prospective, multicentre study, patients scheduled for elective […]

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Uncategorized Published - 25 May, 2021    By - Dr Clemens
Informed Consent: Substance and Signature

Robert Morton, CPHRM, CPPS, Assistant Vice President, Department of Patient Safety and Risk Management The Doctors Company For decades, consent documents have helped protect physicians against the claims of dissatisfied patients. Times have changed, however, and modern medicine requires a more complex and complete acknowledgment of both the patient’s and the physician’s rights and responsibilities […]

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Uncategorized Published - 25 May, 2021    By - Dr Clemens
Combined Platelet and Erythrocyte Salvage: Evaluation of a New Filtration-based Autotransfusion Device

Authors: Alexandre Mansour, M.D. et al  Anesthesiology May 2021. Background The SAME device (i-SEP, France) is an innovative filtration-based autotransfusion device able to salvage and wash both red blood cells and platelets. This study evaluated the device performances using human whole blood with the hypothesis that the device will be able to salvage platelets while […]

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Uncategorized Published - 25 May, 2021    By - Dr Clemens
Single dose perioperative intrathecal ketamine as an adjuvant to intrathecal bupivacaine

DG Journal Club Samantha Sohnen, Oonagh Dowling et al. J Clin Anesth. 2021 May STUDY OBJECTIVE To identify whether adding intrathecal ketamine to intrathecal bupivacaine prolongs the time to first analgesic request in adult humans. DESIGN A meta-analysis of randomized controlled trials in humans. SETTING The majority of data was obtained in an operating room […]

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Uncategorized Published - 25 May, 2021    By - Dr Clemens
Efficacy of different infusion rates of oxytocin for maintaining uterine tone during elective caesarean section

DG Journal Club Medha Mohta, Rohit B Chowdhury et al. Anaesth Intensive Care. 2021 May Most research in this field has focused on finding oxytocin doses for initiating uterine contractions. Only limited data are available regarding the optimal rate of oxytocin infusion to maintain adequate uterine tone. This randomised, double blind study included 120 healthy […]

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Uncategorized Published - 24 May, 2021    By - Dr Clemens
Postoperative Hematocrit and Adverse Outcomes in Pediatric Cardiac Surgery Patients

AUTHORS: Long, Justin B. MD et al Anesthesia & Analgesia: March 15, 2021 BACKGROUND: We sought to examine potential associations between pediatric postcardiac surgical hematocrit values and postoperative complications or mortality. METHODS: A retrospective, cross-sectional study from the Society of Thoracic Surgeons Congenital Heart Surgery Database (STS-CHSD) and Congenital Cardiac Anesthesia Society Database Module (2014–2019) was […]

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Uncategorized Published - 24 May, 2021    By - Dr Clemens
Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium

AUTHORS: Wang, Man-Ling MD et al Anesthesia & Analgesia: March 15, 2021 BACKGROUND: Postoperative delirium is common among older surgical patients and may be associated with anesthetic management during the perioperative period. The aim of this study is to assess whether intravenous midazolam, a short-acting benzodiazepine used frequently as premedication, increased the incidence of postoperative delirium. […]

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Uncategorized Published - 24 May, 2021    By - Dr Clemens
Association of Gestational Age with Postpartum Hemorrhage

Authors: Alexander J. Butwick, M.B.B.S., F.R.C.A., M.S. et al Anesthesiology June 2021, Vol. 134, 874–886. Background Risk factors for postpartum hemorrhage, such as chorioamnionitis and multiple gestation, have been identified in previous epidemiologic studies. However, existing data describing the association between gestational age at delivery and postpartum hemorrhage are conflicting. The aim of this study was […]

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Uncategorized Published - 24 May, 2021    By - Dr Clemens
Postoperative Pulmonary Complications’ Association with Sugammadex versus Neostigmine

Authors: Gen Li, M.Stat et al  Anesthesiology June 2021, Vol. 134, 862–873. Background Postoperative residual neuromuscular blockade related to nondepolarizing neuromuscular blocking agents may be associated with pulmonary complications. In this study, the authors sought to determine whether sugammadex was associated with a lower risk of postoperative pulmonary complications in comparison with neostigmine. Methods Adult patients […]

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Uncategorized Published - 24 May, 2021    By - Dr Clemens
Point-of-Care Lung Ultrasound Pattern in Healthy Parturients: Prevalence of Pulmonary Interstitial Syndrome Following Vaginal Delivery, Elective and Unplanned Intrapartum Cesarean Delivery

AUTHORS: Macias, Paul MD, MS, RD et al Anesthesia & Analgesia: March 15, 2021 BACKGROUND: Pregnancy-related cardiovascular physiologic changes increase the likelihood of pulmonary edema, with the risk of fluid extravasating into the pulmonary interstitium being potentially at a maximum during the early postpartum period. Data on the impact of labor and peripartum hemodynamic strain on […]

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