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Uncategorized Published - 4 June, 2021    By - Dr Clemens
Association of Delirium during Critical Illness With Mortality

AUTHORS: Hughes, Christopher G. MD, MS et al Anesthesia & Analgesia: April 2021 BACKGROUND: The temporal association of delirium during critical illness with mortality is unclear, along with the associations of hypoactive and hyperactive motoric subtypes of delirium with mortality. We aimed to evaluate the relationship of delirium during critical illness, including hypoactive and hyperactive motoric […]

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Uncategorized Published - 4 June, 2021    By - Dr Clemens
Local Anesthetics Inhibit Transient Receptor Potential Vanilloid Subtype 3 Channel Function in Xenopus Oocytes

AUTHORS: Horishita, Reiko MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1756-1767 BACKGROUND:  The transient receptor potential vanilloid subtype 3 (TRPV3) channel is activated by innocuous temperature and several chemical stimuli. It is proposed to be involved in pathological pain development and is therefore considered a potential target […]

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Uncategorized Published - 3 June, 2021    By - Dr Clemens
The Evaluation of a Noninvasive Respiratory Volume Monitor in Mechanically Ventilated Neonates and Infants

AUTHORS: Atkinson, Douglas B. MD et al Anesthesia & Analgesia: April 2021 BACKGROUND: The respiratory volume monitor (RVM) (ExSpiron, Respiratory Motion Inc, Watertown, MA) uses thoracic impedance technology to noninvasively and continuously measure tidal volume (TV), respiratory rate (RR), and minute ventilation (MV). We aimed to validate the accuracy of the RVM to assess ventilation in […]

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Uncategorized Published - 3 June, 2021    By - Dr Clemens
Anesthetic Management of Von Willebrand Disease in Pregnancy

AUTHORS: Reale, Sharon C. MD et al Anesthesia & Analgesia: April 2021 BACKGROUND: Although Von Willebrand disease (vWD) is the most common heritable bleeding disorder, there are limited reports regarding the safety of neuraxial anesthesia in the obstetric population and no definitive guidelines specifying recommended pretreatment or therapies for patients with vWD. The aim of this […]

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Uncategorized Published - 3 June, 2021    By - Dr Clemens
Preparing Anesthesiology Residents for Operating Room Communication Challenges: A New Approach for Conflict Resolution Training

AUTHORS: Birnbach, David J. MD, MPH et al Anesthesia & Analgesia: April 2021 BACKGROUND: The hierarchical culture in high-stake areas such as operating rooms (ORs) may create volatile communication challenges. This unfunded exploratory study sought to establish whether a conflict resolution course was effective in preparing anesthesiology residents to handle and deescalate disagreements that may […]

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Uncategorized Published - 3 June, 2021    By - Dr Clemens
Propofol for Induction and Maintenance of Anesthesia in Patients With Brugada Syndrome

AUTHORS: Flamée, Panagiotis MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1645-1653 BACKGROUND:  Propofol administration in patients with Brugada syndrome (BrS) is still a matter of debate. Despite lacking evidence for its feared arrhythmogenicity, up to date, expert cardiologists recommend avoiding propofol. The main aim of this study […]

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Uncategorized Published - 3 June, 2021    By - Dr Clemens
An Assessment of Anesthesia Capacity in Liberia: Opportunities for Rebuilding Post-Ebola

AUTHORS: Odinkemelu, Didi S. MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1727-1737 BACKGROUND:  The health system of Liberia, a low-income country in West Africa, was devastated by a civil war lasting from 1989 to 2003. Gains made in the post-war period were compromised by the 2014–2016 Ebola […]

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Uncategorized Published - 2 June, 2021    By - Dr Clemens
Effect of Intravenous Acetaminophen on Mean Arterial Blood Pressure

AUTHORS: Bravo, Mauro MD et al Anesthesia & Analgesia: April 2021 BACKGROUND: Acetaminophen is commonly used as part of multimodal analgesia for acute pain. The intravenous formulation offers a more predictable bioavailability compared to oral and rectal acetaminophen. There have been reports of hypotension with intravenous acetaminophen attributable to centrally mediated and vasodilatory effects. We tested […]

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Uncategorized Published - 2 June, 2021    By - Dr Clemens
Preclinical Proficiency-Based Model of Ultrasound Training

AUTHORS: Fatima, Huma MD et al Anesthesia & Analgesia: April 2021 BACKGROUND: Graduate medical education is being transformed from a time-based training model to a competency-based training model. While the application of ultrasound in the perioperative arena has become an expected skill set for anesthesiologists, clinical exposure during training is intermittent and nongraduated without a structured […]

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Uncategorized Published - 2 June, 2021    By - Dr Clemens
Association Between Antifibrinolytic Therapy and Perioperative Outcomes in Patients With Coronary Artery Stents Undergoing Noncardiac Surgery

AUTHORS: Boswell, Michael R. MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1635-1644 BACKGROUND:  Patients with existing coronary artery stents are at an increased risk for major adverse cardiac events (MACEs) when undergoing noncardiac surgery (NCS). Although the use of antifibrinolytic (AF) therapy in NCS has significantly increased […]

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