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Uncategorized Published - 7 December, 2021    By - Dr Clemens
Effect of Global Ventilation to Perfusion Ratio, for Normal Lungs, on Desflurane and Sevoflurane Elimination Kinetics

Authors: James E. Baumgardner, M.D., Ph.D., M.D. et al  Anesthesiology December 2021, Vol. 135, 1042–1054. Background Kinetics of the uptake of inhaled anesthetics have been well studied, but the kinetics of elimination might be of more practical importance. The objective of the authors’ study was to assess the effect of the overall ventilation/perfusion ratio (VA/Q), […]

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Uncategorized Published - 7 December, 2021    By - Dr Clemens
Discovering Alignment: Building on What the Pandemic Taught Us About Clinician Well-Being

Authoir: Natalya S. Hasan-Hill, MD ASA Monitor December 2021, Vol. 85, 24–25. In “Stumbling Into the Next Stage of Your Pandemic Life,” psychotherapist Lindsey Antin describes the complicated psychology of “returning” (asamonitor.pub/3lv1nYo). For some people, returning means coming out of quarantine and going back to their work or practice in person. That doesn’t apply to […]

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Uncategorized Published - 6 December, 2021    By - Dr Clemens
Spinal Anesthesia with Targeted Sedation based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium

Authors: Charles H. Brown, IV, M.D., M.H.S. et al  Anesthesiology December 2021, Vol. 135, 992–1003. Background Reducing depth of anesthesia and anesthetic exposure may help prevent delirium, but trials have been conflicting. Most studies were conducted under general anesthesia or in cognitively impaired patients. It is unclear whether reducing depth of anesthesia beyond levels consistent […]

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Uncategorized Published - 6 December, 2021    By - Dr Clemens
Carbon Footprint of General, Regional, and Combined Anesthesia for Total Knee Replacements

Authors: Forbes McGain, F.A.N.Z.C.A, F.C.I.C.M., Ph.D. et al  Anesthesiology December 2021, Vol. 135, 976–99 Background Health care itself contributes to climate change. Anesthesia is a “carbon hotspot,” yet few data exist to compare anesthetic choices. The authors examined the carbon dioxide equivalent emissions associated with general anesthesia, spinal anesthesia, and combined (general and spinal anesthesia) […]

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Uncategorized Published - 6 December, 2021    By - Dr Clemens
Poor Correlation between Diaphragm Thickening Fraction and Transdiaphragmatic Pressure in Mechanically Ventilated Patients and Healthy Subjects

Authors: Thomas Poulard, M.Sc. et al  Anesthesiology November 2021. Background The relationship between the diaphragm thickening fraction and the transdiaphragmatic pressure, the reference method to evaluate the diaphragm function, has not been clearly established. This study investigated the global and intraindividual relationship between the thickening fraction of the diaphragm and the transdiaphragmatic pressure. The authors […]

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Uncategorized Published - 6 December, 2021    By - Dr Clemens
Pain and Opioid Consumption and Mobilization after Surgery

Authors: Eva Rivas, M.D. et al  Anesthesiology November 2021. Background Early mobilization is incorporated into many enhanced recovery pathways. Inadequate analgesia or excessive opioids may restrict postoperative mobilization. The authors tested the hypotheses that in adults recovering from abdominal surgery, postoperative pain and opioid consumption are inversely related to postoperative mobilization, and that postoperative mobilization […]

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Uncategorized Published - 6 December, 2021    By - Dr Clemens
Wither COVID? How the Pandemic Ends

Authors: Richard Simoneaux and Steven L. Shafer, MD, FASA ASA Monitor December 2021, Vol. 85, 1–5. In January 2021, Public Health England initiated a comprehensive strategy to monitor vaccination efficacy and safety (asamonitor.pub/3vnt0G9). Since then, Public Health England has monitored vaccination, serology (collected from blood doners), and outcomes (hospitalization and death). The serological analysis involved testing 250 […]

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Uncategorized Published - 3 December, 2021    By - Dr Clemens
Plasma Volume Expansion and Fluid Kinetics of 20% Albumin During General Anesthesia and Surgery Lasting for More Than 5 Hours

AUTHORS: Gunnström, Michaela MD Anesthesia & Analgesia: November 2021 BACKGROUND: Intraoperative administration of crystalloid for plasma volume expansion may be reduced by use of hyperoncotic albumin. However, the degree of plasma volume expansion with administration of 20% albumin is poorly quantitated. We estimated the amount of volume expansion attributable to 20% albumin administration in patients undergoing […]

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Uncategorized Published - 3 December, 2021    By - Dr Clemens
Comparison of Intra and Post-operative Sedation efficacy of Dexmedetomidine-Midazolam and Dexmedetomidine-Propofol for Major Abdominal Surgery

DG Journal Club AUTHORS: Yuanyuan Gao, Fei Yan Curr Drug Metab. 2021 Nov 3 BACKGROUND The effectiveness and side effects of dexmedetomidine (DEX) in combination with midazolam and propofol have not been comparatively studied in a single clinical trial as sedative agents to general anesthesia before. OBJECTIVE The objective of this study is to compare […]

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Uncategorized Published - 3 December, 2021    By - Dr Clemens
Comparison of Oral Loading Dose to Intravenous Acetaminophen in Children for Analgesia After Tonsillectomy and Adenoidectomy

AUTHORS: Lammers, Cathy R. MD et al Anesthesia & Analgesia: December 2021 – Volume 133 – Issue 6 – p 1568-1576 BACKGROUND:  Acetaminophen is a frequently used adjunct analgesic in pediatric patients undergoing tonsillectomy and adenoidectomy. We compared opioid administration following preoperative intravenous (IV) or oral acetaminophen in addition to a standard multimodal regimen to test […]

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