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AUTHORS: Gunnström, Michaela MD Anesthesia & Analgesia: November 2021 BACKGROUND: Intraoperative administration of crystalloid for plasma volume expansion may be reduced by use of hyperoncotic albumin. However, the degree of plasma volume expansion with administration of 20% albumin is poorly quantitated. We estimated the amount of volume expansion attributable to 20% albumin administration in patients undergoing […]
Read MoreDG Journal Club AUTHORS: Yuanyuan Gao, Fei Yan Curr Drug Metab. 2021 Nov 3 BACKGROUND The effectiveness and side effects of dexmedetomidine (DEX) in combination with midazolam and propofol have not been comparatively studied in a single clinical trial as sedative agents to general anesthesia before. OBJECTIVE The objective of this study is to compare […]
Read MoreAUTHORS: Lammers, Cathy R. MD et al Anesthesia & Analgesia: December 2021 – Volume 133 – Issue 6 – p 1568-1576 BACKGROUND: Acetaminophen is a frequently used adjunct analgesic in pediatric patients undergoing tonsillectomy and adenoidectomy. We compared opioid administration following preoperative intravenous (IV) or oral acetaminophen in addition to a standard multimodal regimen to test […]
Read MoreThis is for our readers that treat patients in the ICU. DG Alerts Findings from a study published in the Journal of Endocrinological Investigation suggest an association between testosterone deficiency and high risk of acute hypoxemic respiratory failure at admission, need of oxygen support and mortality during hospital stay in adult males with coronavirus disease 2019 (COVID-19). […]
Read MoreAuthor: Michael Walter Cardiovascular Business Journal Percutaneous coronary intervention (PCI) guided by fractional flow reserve (FFR) was not found to be noninferior to coronary artery bypass grafting (CABG) for patients with three-vessel coronary artery disease (3V-CAD), according to new research presented Nov. 4 at TCT 2021. The analysis, which was also published in the New England […]
Read MoreAuthor: Robert Pearl, MD ASA Monitor December 2021, Vol. 85, 25–26. Editor’s note: The following article contains observations and insights from Dr. Pearl that are more thoroughly explored on his website (robertpearlmd.com) and in his 2021 book “Uncaring: How the Culture of Medicine Kills Doctors & Patients.” Every doctor knows that properly diagnosing an ailment […]
Read MoreAUTHORS: Jung, Jaewoong MD et al Anesthesia & Analgesia: December 2021 – Volume 133 – Issue 6 – p 1624-1632 BACKGROUND: Previous research has not evaluated the potential effect of transversus abdominis plane (TAP) block on quality of recovery following laparoscopic cholecystectomy. Therefore, we investigated whether addition of the bilateral subcostal and lateral TAP (bilateral dual […]
Read MoreAUTHORS: Koch, Susanne MD, PhD et al Anesthesia & Analgesia: December 2021 – Volume 133 – Issue 6 – p 1598-1607 BACKGROUND: Intraoperative electroencephalography (EEG) signatures related to the development of postoperative delirium (POD) in older patients are frequently studied. However, a broad analysis of the EEG dynamics including preoperative, postinduction, intraoperative and postoperative scenarios and […]
Read MoreAUTHORS: Zhou, Yang MD et al Anesthesia & Analgesia: December 2021 – Volume 133 – Issue 6 – p 1588-1597 BACKGROUND: Depressive symptoms occur in over 40% of neurosurgical patients during the perioperative period. However, no measure has been suggested to have a rapid effect on depressive surgical patients during increasingly shorter stays in the hospital. […]
Read MoreAUTHORS: Sequera-Ramos, Luis MD et al Anesthesia & Analgesia: December 2021 – Volume 133 – Issue 6 – p 1559-1567 BACKGROUND: Beckwith-Wiedemann syndrome (BWS) is the most common congenital overgrowth disorder with an incidence of approximately 1 in 10,000 live births. The condition is characterized by lateralized overgrowth, abdominal wall defects, macroglossia, and predisposition to malignancy. […]
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