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Uncategorized Published - 2 May, 2022    By - Dr Clemens
Center Variation in Use of Preoperative Dual Antiplatelet Therapy and Platelet Function Testing at the Time of Coronary Artery Bypass Grafting in Maryland

AUTHORS: Hensley, Nadia B. MD et al Anesthesia & Analgesia: April 2022 BACKGROUND: Patients presenting with acute coronary syndrome are administered a P2Y12 inhibitor and aspirin before coronary catheterization to prevent further myocardial injury from thrombosis. Guidelines recommend a standard waiting period between the time patients are administered dual antiplatelet therapy (DAPT) and elective cardiac surgery. Since […]

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Uncategorized Published - 2 May, 2022    By - Dr Clemens
Identification of Foramen Ovale With H-Figure Fluoroscopic Landmark Improves Treatment Outcomes in Idiopathic Trigeminal Neuralgia

AUTHORS: He, Liang-Liang MD et al Anesthesia & Analgesia: April 2022 BACKGROUND: Because it is traditionally difficult and time-consuming to identify the foramen ovale (FO) with fluoroscopy, we recently developed the H-figure method to acquire fluoroscopic view of FO with shorter procedure time and less radiation. However, the impact of such an H-figure approach on the […]

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Uncategorized Published - 2 May, 2022    By - Dr Clemens
Postoperative pain as a risk factor for stiff knee following total knee arthroplasty and excellent patientreported outcomes after manipulation under anesthesia

DG Journal Club AUTHORS: Mikko T Rantasalo et al Acta Orthop. 2022 Apr 14; 93 432-437 BACKGROUND AND PURPOSE Manipulation under anesthesia (MUA) is the first-choice treatment for stiffness following total knee arthroplasty (TKA) unresponsive to pain management and physiotherapy. Some of the predisposing factors and patient-reported outcome measures (PROMs) following MUA remain poorly studied. […]

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Uncategorized Published - 2 May, 2022    By - Dr Clemens
Should We Use Race-Based Corrections for Spirometry?

NEJM Journal Watch David J. Amrol, MD, reviewing Elmaleh-Sachs A et al.  Am J Respir Crit Care Med 2022 Mar 15 Schluger NW.  This practice doesn’t help predict adverse respiratory events. When interpreting spirometry, published normative values differ among various ethnic groups. In the U.S., spirometers use either race-specific reference values based on the National Health […]

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Uncategorized Published - 29 April, 2022    By - Dr Clemens
Regional Anesthesia Associated With Decreased Inpatient and Outpatient Opioid Demand in Tibial Plateau Fracture Surgery

AUTHORS: Cunningham, Daniel J. MD, MHSc et al Anesthesia & Analgesia: May 2022 – Volume 134 – Issue 5 – p 1072-1081 BACKGROUND:  Regional anesthesia (RA) has been used to reduce pain and opioid usage in elective orthopedic surgery. The hypothesis of this study was that RA would be associated with decreased opioid demand in tibial […]

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Uncategorized Published - 29 April, 2022    By - Dr Clemens
The First Derivative of the Electroencephalogram Facilitates Tracking of Electroencephalographic Alpha Band Activity During General Anesthesia

AUTHORS: Obert, David P. MD et al Anesthesia & Analgesia: May 2022 – Volume 134 – Issue 5 – p 1062-1071 BACKGROUND:  Intraoperative neuromonitoring can help to navigate anesthesia. Pronounced alpha oscillations in the frontal electroencephalogram (EEG) appear to predict favorable perioperative neurocognitive outcomes and may also provide a measure of intraoperative antinociception. Monitoring the presence […]

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Uncategorized Published - 29 April, 2022    By - Dr Clemens
Effects of Sevoflurane-Propofol–Balanced Anesthesia on Flash Visual Evoked Potential Monitoring in Spine Surgery

AUTHORS: Ma, Jiajia MD et al  Anesthesia & Analgesia: May 2022 – Volume 134 – Issue 5 – p 1054-1061 BACKGROUND:  Intraoperative flash visual evoked potential (FVEP) can be used to monitor visual function during spine surgery. However, it is limited due to the previous perception of its sensitivity to inhalation anesthesia. We conducted this trial […]

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Uncategorized Published - 29 April, 2022    By - Dr Clemens
Novel Opioid Analgesics for the Development of Transdermal Opioid Patches That Possess Morphine-Like Pharmacological Profiles Rather Than Fentanyl

AUTHORS: Komatsu, Akane MD et al Anesthesia & Analgesia: May 2022 – Volume 134 – Issue 5 – p 1082-1093 BACKGROUND:  Transdermal fentanyl is widely used in the treatment of severe pain because of convenience, safety, and stable blood concentrations. Nevertheless, patients often develop tolerance to fentanyl, necessitating the use of other opioids; transdermal buprenorphine patch […]

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Uncategorized Published - 29 April, 2022    By - Dr Clemens
Intensive Care in Sub-Saharan Africa: A National Review of the Service Status in Ethiopia

AUTHORS: Kifle, Fitsum MSc et al Anesthesia & Analgesia: May 2022 – Volume 134 – Issue 5 – p 930-937 BACKGROUND:  The burden of critical illness in low-income countries is high and expected to rise. This has implications for wider public health measures including maternal mortality, deaths from communicable diseases, and the global burden of disease […]

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Uncategorized Published - 28 April, 2022    By - Dr Clemens
Sugammadex Versus Neostigmine for Reversal of Residual Neuromuscular Blocks After Surgery

AUTHORS: Ruetzler, Kurt MD, FAHA et al Anesthesia & Analgesia: May 2022 – Volume 134 – Issue 5 – p 1043-1053 BACKGROUND:  Sugammadex and neostigmine given to reverse residual neuromuscular blockade can cause side effects including bradycardia, anaphylaxis, bronchospasm, and even cardiac arrest. We tested the hypothesis that sugammadex is noninferior to neostigmine on a composite […]

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