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Survival rates for high-risk surgeries diverge greatly from hospital to hospital, a new report indicates, underscoring the fact that much work still needs to be done to improve patient outcomes. In the analysis, the nonprofit Leapfrog Group used 2013 data from 1,500 hospitals to determine “predicted survival” rates for abdominal aortic aneurysm (AAA) repairs, aortic valve replacements (AVR), esophagectomy […]
Read MoreAuthors: Spertus J., N Engl J Med 2015 Mar 12; 372:1069 A randomized trial suggests no significant differences between liberal and restricted thresholds — but leaves room for debate. The optimal hemoglobin threshold for transfusion after surgical procedures is a longstanding controversy. Observational studies of patients undergoing cardiac surgery have suggested worse outcomes with liberal transfusion thresholds […]
Read MoreAuthors: King JT Jr et al., JAMA Surg 2015 Feb 25; Thirty-day mortality, although relatively low, was still higher than for HIV-uninfected patients. Now that HIV-infected individuals have a near-normal life expectancy, they are increasingly likely to undergo surgical procedures. How do their short-term surgical outcomes compare with those of HIV-uninfected patients? To answer this question, investigators studied […]
Read MoreAuthors: Whitley RJ., Clin Infect Dis 2015 Mar 15; 60:910 This is for our providers that take care of chronic pain patients. After 10 years, vaccination lost most of its power. Short-term follow-up of participants in placebo-controlled studies of the herpes zoster (HZ) vaccine confirmed that the vaccine was efficacious for at least 5 years (NEJM JW […]
Read MoreThe US Food and Drug Administration (FDA) has approved the extended-release (ER) single-entity opioid analgesic hydrocodone bitartrate (Hysingla ER, Purdue Pharma) with abuse-deterrent properties in line with the FDA’s 2013 draft guidance to industry, the agency announced. “Hysingla ER has properties that are expected to reduce, but not totally prevent, abuse of the drug when […]
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