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Uncategorized Published - 14 July, 2015    By - Dr Clemens
The ED90 of Prophylactic Oxytocin Infusion After Delivery of the Placenta During Cesarean Delivery in Laboring Compared with Nonlaboring Women: An Up-Down Sequential Allocation Dose-Response Study

Anesthesia & Analgesia: July 2015 Volume 121 pages 159-164 Authors: Lavoie, Anne MD et al BACKGROUND: Prophylactic administration of oxytocin as a part of active management of the third stage of labor reduces the risk of postpartum hemorrhage. Prophylactic oxytocin is often administered as an infusion rather than a bolus. The aim of the current […]

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Uncategorized Published - 14 July, 2015    By - Dr Clemens
Sedation-Analgesia with Propofol and Remifentanil: Concentrations Required to Avoid Gag Reflex in Upper Gastrointestinal Endoscopy

Anesthesia & Analgesia: July 2015 Volume 121 page 90-96 Authors: Borrat, Xavier MD  et al BACKGROUND: The purpose of this study was to identify optimal target propofol and remifentanil concentrations to avoid a gag reflex in response to insertion of an upper gastrointestinal endoscope. METHODS: Patients presenting for endoscopy received target-controlled infusions (TCI) of both […]

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Uncategorized Published - 14 July, 2015    By - Dr Clemens
The Incidence of Perioperative Hypersensitivity Reactions: A Single-Center, Prospective, Cohort Study

Anesthesia & Analgesia: July 2015 Volume 121 page 117-123 Authors: Berroa, Felicia MD, PhD et al BACKGROUND: The incidence of perioperative hypersensitivity reactions, which can be life-threatening, ranges from 1 in 20,000 to 1 in 1361. These reactions are usually classified as IgE or non-IgE mediated. The aim of this study was to determine the […]

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Uncategorized Published - 13 July, 2015    By - Dr Clemens
A Multicenter Evaluation of a Closed-Loop Anesthesia Delivery System: A Randomized Controlled Trial

Published in Anesthesia & Analgesia: April 2015 Authors: Puri, Goverdhan D. MD, PhD et al BACKGROUND: Closed-loop systems for anesthesia delivery have been shown to outperform traditional manual control in different clinical settings. The present trial was aimed at evaluating the feasibility and efficacy of Bispectral Index (BISTM)-guided closed-loop anesthesia delivery system (CLADS) in comparison […]

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Uncategorized Published - 13 July, 2015    By - Dr Clemens
The Effect of Adding a Background Infusion to Patient-Controlled Epidural Labor Analgesia on Labor, Maternal, and Neonatal Outcomes: A Systematic Review and Meta-Analysis

Anesthesia & Analgesia: April 2015  Issue 1 page 149-158 Authors: Heesen, Michael MD et al BACKGROUND: Patient-controlled epidural analgesia (PCEA) has gained popularity, but it is still unclear whether adding a background infusion confers any benefit. METHODS: A systematic literature search in PubMed, Embase, CINAHL, LILACS, CENTRAL, Clinicaltrials.gov, and ISI WOS was performed to identify […]

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