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Uncategorized Published - 4 May, 2015    By - Dr Clemens
Error Modelling in Anaesthesia

Published in Br J Anaesth. 2014;113(6):905-906. Authors: J. Moloney Accidents in complex systems occur through the concatenation of multiple factors; each may be necessary, but only when all are present are conditions sufficient to produce an accident. In 1990, James Reason, then a professor of Psychology at the University of Manchester, provided a crucial contribution to […]

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Uncategorized Published - 4 May, 2015    By - Dr Clemens
Multiple Epidural Steroid Injections and Body Mass Index Linked With Occurrence of Epidural Lipomatosis

Published in BMC Anesthesiol. 2014;14(70) Authors: Rafael Jaimes, Angelo G Rocco Background: Epidural lipomatosis (EL) is an increase of adipose tissue, normally occurring in the epidural space, sufficient to distort the thecal sac and compress neural elements. There is a lack of knowledge of risk factors, impact on patient’s symptoms, and its possible association with epidural […]

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Uncategorized Published - 1 May, 2015    By - Dr Clemens
Scant Evidence for Long-Term Opioid Therapy in Chronic Pain

There is insufficient evidence to determine the effectiveness of long-term opioid therapy for improving chronic pain, but emerging data support a dose-dependent risk for serious harms, such as overdose, mortality, and possibly fractures and cardiovascular events, according to a new review. Most opioid-related studies lasted less than 12 weeks (and many less than 6 weeks), […]

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Uncategorized Published - 1 May, 2015    By - Dr Clemens
Efficacy and tolerability of low-dose oral prolonged-release oxycodone/naloxone for chronic nononcological pain in older patients

Published in Clin Interv Aging. 2014 Dec 16;10:1-11 Authors: Guerriero F et al PURPOSE: Chronic pain is highly prevalent in older adults. Increasing evidence indicates strong opioids as a valid option for chronic pain management in geriatrics. The aim of this study was to evaluate efficacy and safety of low-dose oral prolonged-release oxycodone-naloxone (OXN-PR) in […]

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Uncategorized Published - 1 May, 2015    By - Dr Clemens
Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

Published in Lancet Neurol. 2015 Feb;14(2):162-73 Authors: Finnerup NB et al BACKGROUND: New drug treatments, clinical trials, and standards of quality for assessment of evidence justify an update of evidence-based recommendations for the pharmacological treatment of neuropathic pain. Using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE), we revised the Special Interest Group on […]

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