AUTHORS: Deljou, Atousa MD et al Anesthesia & Analgesia 136(6):p 1154-1163, June 2023. BACKGROUND: Residual deep sedation during anesthesia recovery may predict postoperative complications. We examined the incidence and risk factors for deep sedation after general anesthesia. METHODS: We retrospectively reviewed health records of adults who underwent procedures with general anesthesia and were admitted to the […]

Postoperative Outcomes in Elderly Patients Undergoing Cardiac Surgery With Preoperative Cognitive Impairment
AUTHORS: Au, Emily BSc et al Anesthesia & Analgesia 136(6):p 1016-1028, June 2023. BACKGROUND: Older patients with preoperative cognitive impairment are at risk for increased postoperative complications after noncardiac surgery. This systematic review and meta-analysis aimed to determine the association between preoperative cognitive impairment and dementia and postoperative outcomes in older surgical patients after cardiac surgery. […]
Transnasal Humidified Rapid Insufflation Ventilatory Exchange Augments Oxygenation in Children With Juvenile Onset Recurrent Respiratory Papillomatosis During Surgery
AUTHORS: Lei, Guiyu MD et al Anesthesia & Analgesia 137(3):p 578-586, September 2023. BACKGROUND: Evidence is lacking regarding the efficacy of transnasal humidified rapid insufflation ventilatory exchange (THRIVE) in tubeless anesthesia, especially in pediatric patients. This study aimed to evaluate the use of THRIVE for juvenile onset recurrent respiratory papillomatosis (JORRP) patients. METHODS: Twenty-eight children aged […]
Examining Subjective Psychological Experiences of Postoperative Delirium in Older Cardiac Surgery Patients
AUTHORS: Cohen, Caitlin L. BPsych (Hons) et al Anesthesia & Analgesia 136(6):p 1174-1181, June 2023. BACKGROUND: Postoperative delirium (POD) is an acute syndrome including inattention and impaired cognition that affects approximately 42% of older cardiac surgical patients. POD is linked to adverse outcomes including morbidity, mortality, and further cognitive decline. Less is known about the subjective […]
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Updates for Pain Management
Author: Rita Astani President—Anesthesia Coronis Health Anesthesia According to a source on the history of idioms, there was a custom in ancient times of pouring a cauldron of boiling water onto unwelcome intruders or enemy soldiers from an upper window or castle wall to encourage their retreat. From at least the 1600s, to be “in […]
Effect of Tulobuterol Patch Versus Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies
AUTHORS: Kim, Eun-Hee MD, PhD et al Anesthesia & Analgesia 136(6):p 1067-1074, June 2023. BACKGROUND: Perioperative respiratory adverse events are common in children. We aimed to evaluate the effect of the transdermal β-2 agonist, tulobuterol, compared with that of placebo on the incidence of perioperative respiratory adverse events in pediatric patients undergoing tonsillectomy. METHODS: In this […]
Sociodemographic Disparities in Postoperative Nausea and Vomiting
AUTHORS: Lee, Donaldson C. MD et al Anesthesia & Analgesia 137(3):p 665-675, September 2023. BACKGROUND: Postoperative nausea and vomiting (PONV) prophylaxis is consistently considered a key indicator of anesthesia care quality. PONV may disproportionately impact disadvantaged patients. The primary objectives of this study were to examine the associations between sociodemographic factors and the incidence of PONV […]
Sleep Fragmentation, Electroencephalographic Slowing, and Circadian Disarray in a Mouse Model for Intensive Care Unit Delirium
AUTHORS: Dulko, Elzbieta MS et al Anesthesia & Analgesia 137(1):p 209-220, July 2023. BACKGROUND: We aimed to further validate our previously published animal model for delirium by testing the hypothesis that in aged mice, Anesthesia, Surgery and simulated ICU conditions (ASI) induce sleep fragmentation, electroencephalographic (EEG) slowing, and circadian disarray consistent with intensive care unit (ICU) […]
Outpatient Treatment With Gabapentin in Women With Severe Acute Pain After Cesarean Delivery Is Ineffective
AUTHORS: Fowler, Cedar MD, PhD et al Anesthesia & Analgesia 136(6):p 1122-1132, June 2023. BACKGROUND: Most of the 1.1 million women who deliver by cesarean in the United States each year have an uncomplicated recovery. However, severe pain resistant to standard multimodal therapy within the first days after surgery is associated with an increased risk for […]