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Anesthesiology Published - 5 May, 2026    By - Dr Clemens
Can Fasting Reprogram Chronic Pain?

Author: Horst Gross Medscape Fasting alters core physiologic processes — including inflammation regulation, energy metabolism, and neuronal plasticity — and these shifts can change the trajectory of chronic pain, particularly when peripheral and central mechanisms interact. At the German Pain and Palliative Care Days 2026, Louise Reisner-Sénélar, MD, medical director at the Schmerzzentrum-Wiesbaden (Pain Centre Wiesbaden), […]

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Anesthesiology Published - 5 May, 2026    By - Dr Clemens
Differential effects of phenylephrine on brain versus skeletal muscle microvascular perfusion: an in vivo laboratory study using translational rodent models

Authors: Jiang H et al. Canadian Journal of Anesthesia, April 24, 2026 This in vivo translational rodent study examined how phenylephrine (PE), a commonly used vasopressor in anesthesia, differentially affects microvascular perfusion in the brain versus skeletal muscle. Given that intraoperative hypotension is associated with poor outcomes, vasopressors like PE are frequently used to restore […]

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Anesthesiology Published - 4 May, 2026    By - Dr Clemens
The Relationship Between Socioeconomic Status and Emergence Delirium

Authors: Burns K et al. Pediatric Anesthesia, April 27, 2026 This retrospective cohort study examined the relationship between socioeconomic status and emergence delirium (ED) in pediatric patients undergoing common outpatient procedures. Emergence delirium is a well-recognized postoperative phenomenon characterized by altered consciousness, agitation, or hypoactive behavior, particularly in children. While prior research has explored physiologic […]

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Anesthesiology Published - 4 May, 2026    By - Dr Clemens
Esmolol as an Adjunct in Multimodal Anesthesia

Authors: Neto EDS et al. Anesthesia & Analgesia, 142(5):882–897, May 2026 This systematic review and meta-analysis evaluates the effectiveness of Esmolol as an adjunct in multimodal anesthesia, specifically focusing on its opioid-sparing and analgesic effects. Unlike prior reviews, this analysis included only placebo-controlled randomized trials to improve the reliability and generalizability of findings. A total […]

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Anesthesiology Published - 4 May, 2026    By - Dr Clemens
Comparison of a gamified versus standard virtual reality simulator to teach ultrasound-guided regional Anaesthesia

Authors: Vernier T et al. Journal of Clinical Anesthesia, Volume 112, June 2026 This randomized controlled trial evaluated whether adding gamification elements to a virtual reality (VR) simulator improves training outcomes in ultrasound-guided regional anesthesia. Gamification—such as rewards, leaderboards, and performance feedback—is often promoted as a way to enhance learner engagement and retention, but evidence […]

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