AUTHORS: Xu, Li MD, PhD et al Anesthesia & Analgesia: June 2022 – Volume 134 – Issue 6 – p 1215-1228 BACKGROUND: Painful diabetic neuropathy (PDN) is one of the major complications of diabetes mellitus. It is often debilitating and refractory to pharmaceutical therapies. Our goal was to systematically review and evaluate the strength of […]
Read MoreAUTHORS: Brito, Michael A. PhD et al Anesthesia & Analgesia: June 2022 – Volume 134 – Issue 6 – p 1126-1139 BACKGROUND: Neurophysiologic complexity has been shown to decrease during states characterized by a depressed level of consciousness, such as sleep or anesthesia. Conversely, neurophysiologic complexity is increased during exposure to serotonergic psychedelics or subanesthetic doses […]
Read MoreAUTHORS: Dean, Jon G. PhD et al Anesthesia & Analgesia: June 2022 – Volume 134 – Issue 6 – p 1140-1152 BACKGROUND: Cholinergic stimulation of prefrontal cortex (PFC) can reverse anesthesia. Conversely, inactivation of PFC can delay emergence from anesthesia. PFC receives cholinergic projections from basal forebrain, which contains wake-promoting neurons. However, the role of basal […]
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Read MoreAuthors: Lalitha Sundararaman, MD et al ASA Monitor June 2022, Vol. 86, 1–8. Diabetes mellitus is one of the top 10 causes of mortality and morbidity worldwide. Additionally, annual worldwide health care expenditure due to diabetes is $726 billion or more (Diabetes Res Clin Pract 2019;157:107843). Advancements in technologies that support diabetes management have greatly increased […]
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