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Authors: Pieter Simons, MD et al Anesthesiology December 2022. Background Oliceridine is a G protein-biased µ-opioid, a drug class that is associated with less respiratory depression than non-biased opioids, such as morphine. We quantified the respiratory effects of oliceridine and morphine in elderly volunteers. We hypothesized that these opioids differ in their pharmacodynamic behavior, measured […]
Read MoreAuthors: Tomonori Takazawa, M.D., Ph.D. et al Anesthesiology December 2022. Background There are no effective pharmacologic interventions for preventing postoperative cognitive dysfunction in daily practice. Since the antibiotic minocycline is known to suppress postoperative neuroinflammation, this study hypothesized and investigated whether minocycline might have a preventive effect on postoperative cognitive dysfunction after noncardiac surgery. Methods […]
Read MoreAuthor: Tony Mira F1rstNews blog Summary Projecting group revenues into the coming year is a difficult proposition for many practices. At the very least, groups should calculate the likely potential relative to three key factors: case volume, case acuity and unit yield. As we close out 2022, most of our clients are wondering what their […]
Read MoreNEJM Journal Watch Allan S. Brett, MD, reviewing Pfeifer KJ et al. Mayo Clin Proc 2021 Dec Oprea AD et al. Mayo Clin Proc 2022 Feb Oprea AD et al. Mayo Clin Proc 2022 Feb During 2021 and 2022, a multidisciplinary group has issued consensus statements on perioperative management of drugs commonly used in pulmonary, gastroenterology, neurology, psychiatry, and rheumatology practice. Sponsoring […]
Read MoreAuthor: Tony Mira F1rstNews Summary The year-end coding and compliance rule changes have been finalized and widely addressed, but there are always a few smaller actions by federal officials that don’t get as much attention. In this alert, we take a look at some recent rules and […]
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