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What Is Now Available and Efficacious? Authors: J. W. Sear et al Br J Anaesth. 2015;115(3):333-336. Publication, in 2008, of the results of POISE, the largest randomized controlled trial (RCT) of perioperative beta-blockade, confirmed previous studies that had shown beta-blockade to offer cardiac protection in patients with, or at risk for, coronary heart disease.[1] However, this protection […]
Read MoreA Retrospective, Observational Study Authors: Lars Stryhn Bjerregaard et BMC Anesthesiol. 2015;15(91) Background: Despite extensive research, the debate continues as to the optimal way of guiding intraoperative and postoperative fluid therapy. In 2009 we changed our institutional guideline for perioperative fluid therapy in patients undergoing extrapleural pneumonectomy (EPP) and implemented the use of central venous oxygen saturation […]
Read MoreThe United States is facing the worst “man-made epidemic” of opioid abuse in the history of modern medicine, and it is the direct result of poor research and outdated teaching practices, according to a leading pain expert. “There’s been over 200,000 deaths from prescription opioids and many more hundreds of thousands of overdose admissions, and […]
Read MoreAuthors: Aziz MF et al., Anesth Analg 2015 Nov 17; In patients with predicted difficult airways intubated in the operating room, the GlideScope had a higher first-attempt intubation success rate than the C-MAC D-Blade. Video laryngoscopy (VL) improves intubation success in patients with predicted difficult airways primarily by ensuring glottic visualization. While VL with acute-angled devices has been […]
Read MoreAuthors: Karen C. Nanji MD MPH et al Anesthesiology 1 2016, Vol.124, 25-34. Background: The purpose of this study is to assess the rates of perioperative medication errors (MEs) and adverse drug events (ADEs) as percentages of medication administrations, to evaluate their root causes, and to formulate targeted solutions to prevent them. Methods: In this prospective observational study, anesthesia-trained […]
Read MoreThe CDC has proposed 12 recommendations for clinicians prescribing opioids. Among them: When initiating opioid therapy, immediate-release opioids at the lowest effective doses are recommended. Extra precautions should be taken when prescribing at or above 50 morphine milligram equivalents (MME) per day, and doses at or above 90 MME per day generally should be avoided. […]
Read MoreNearly 20 organizations including the Academy have endorsed an updated “consensus statement” from the organization SmartTots calling for more research into the safety of anesthetics and sedatives administered to children younger than 4 years. Some evidence has shown that such exposures in very young animals are associated with impairment in learning ability, behavior and memory. […]
Read MoreA simple blood test taken before surgery may predict how quickly patients recover from their procedure, suggests a new study in the December issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists (ASA). According to the study, identifying a patient’s immune state from blood samples taken before surgery, revealed patterns that may […]
Read MoreThe US Food and Drug Administration (FDA) has approved sugammadex injection (Bridion, Merck) for the reversal of moderate or deep neuromuscular blockade induced by rocuronium or vecuronium during surgery, according to an agency news release. The FDA’s Anesthetic and Analgesic Drug Products Advisory Committee recommended approval of the drug back in November. Sugammadex binds to rocuronium and […]
Read MoreASA Monitor 12 2015, Vol.79, 36-37. Case 2015-12: A Different Point of View A 34-year-old man, newly paraplegic from a gunshot wound, presented for thoracic spine instrumentation. While his ventilatory reserve was poor, his airway was patent in his baseline awake state, and minute ventilation was adequate. After induction with propofol and rocuronium, bag mask ventilation […]
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