Authors: Persson NDA et al. Journal: Anesthesiology, December 12, 2025. DOI: 10.1097/ALN.0000000000005794 SummaryThis preclinical imaging study examined how general anesthetic technique and systemic hyperosmolality influence the distribution of intrathecally administered drugs delivered at the lumbar level. Because lumbar intrathecal drug delivery often fails to achieve therapeutic intracranial concentrations, the investigators explored whether anesthetic choice and […]
Read MoreAuthors: Zelber-Sagi S et al. Journal: Anesthesiology, December 12, 2025. DOI: 10.1097/ALN.0000000000005830 SummaryThis large multicenter retrospective analysis evaluated whether the Fibrosis-4 (FIB-4) score—an inexpensive, routinely available marker of liver fibrosis—is associated with perioperative mortality and complications in patients undergoing general anesthesia who did not have clinically apparent liver disease. Given the high prevalence of metabolic […]
Read MoreAuthors: Padilla A et al. Journal: Anesthesiology, December 16, 2025. DOI: 10.1097/ALN.0000000000005788 SummaryThis multicenter retrospective cohort study examined contemporary anesthetic practice patterns for cesarean hysterectomy in patients with placenta accreta spectrum across U.S. hospitals. Using the Multicenter Perioperative Outcomes Group database, the investigators sought to characterize modes of anesthesia and identify clinical factors associated with […]
Read MoreAuthors: Tong C et al. Journal: Anesthesiology, December 29, 2025. DOI: 10.1097/ALN.0000000000005846 SummaryThis randomized controlled trial evaluated the analgesic efficacy and safety of an ultrasound-guided external oblique intercostal (EOI) plane block with ropivacaine in patients undergoing elective open hepatectomy. The study addressed an important clinical gap for patients in whom epidural or paravertebral analgesia may […]
Read MoreAuthor: Patsy Newitt Becker’s ASC Review As physician employment accelerates, anesthesia leaders say the biggest pressure points are structural rather than clinical. Anesthesiologist Jason Hennes, MD, founder of anesthesia data and scheduling platform Anesthesia Data Services, joined Becker’s to discuss the workforce trends shaping how groups staff, pay and measure productivity. Editor’s note: This interview was edited lightly for clarity and […]
Read MoreAuthors: Hovgaard HL et al. Journal: Anesthesiology, Accepted December 26, 2025. DOI: 10.1097/ALN.0000000000005919 SummaryThis prospective, single-blind randomized controlled trial evaluated whether extending goal-directed fluid therapy (GDFT) into the postoperative period using individualized blood pressure targets improves outcomes after oesophagectomy. Given the high morbidity associated with oesophagectomy and the limitations of traditional GDFT—particularly fixed mean arterial […]
Read MoreAuthors: Donovan AL et al. Journal: Anesthesiology, Accepted December 26, 2025. DOI: 10.1097/ALN.0000000000005920 SummaryThis qualitative focus group study explored how anesthesiologists in academic practice define career fulfillment and navigate competing clinical, academic, and personal demands across different career stages. Given that anesthesiologists report the highest intent to leave academic medicine among medical specialties, the authors […]
Read MoreAuthors: Müller-Wirtz LM et al. Journal: Anesthesiology, Accepted December 18, 2025. DOI: 10.1097/ALN.0000000000005906 SummaryThis post hoc analysis of a large cluster factorial randomized trial evaluated whether intraoperative mechanical power—normalized to predicted body weight—is associated with postoperative oxygenation impairment and pulmonary complications in orthopedic surgical patients. Mechanical power integrates multiple ventilatory variables into a single measure […]
Read MoreAuthors: Furdyna MJ et al. Journal: Anesthesiology, Accepted December 23, 2025. DOI: 10.1097/ALN.0000000000005905 SummaryThis large multicenter retrospective cohort study evaluated the frequency, causes, management, and outcomes of maternal peripartum cardiac arrest occurring during peri-anesthetic care in the United States. Using the Multicenter Perioperative Outcomes Group database, the investigators analyzed more than 778,000 deliveries across 60 […]
Read MoreAuthors: Reme SE et al. Journal: Anesthesiology, December 8, 2025. DOI: 10.1097/ALN.0000000000005821 SummaryThis randomized clinical trial compared the effects of a brief preoperative hypnosis session versus mindfulness on postoperative symptoms in women undergoing breast cancer surgery. Recognizing that breast surgery is frequently associated with fatigue, emotional distress, pain, and nausea—and that preoperative anxiety can worsen […]
Read More