Author: Dr Clemens

Anesthesiology Published - 10 April, 2026    By - Dr Clemens
Illustrating Bayesian Indices of Effect Existence and Practical Significance in Anesthesiology Trials

Authors: Huber M Anesthesiology 144(4):1016–1020, April 2026 Summary:This article introduces Bayesian statistical approaches as a complement to traditional frequentist methods in analyzing randomized controlled trials. It focuses on two key Bayesian indices—probability of direction and region of practical equivalence (ROPE)—to provide a more clinically meaningful interpretation of study results. The probability of direction reflects how […]

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Anesthesiology Published - 10 April, 2026    By - Dr Clemens
Returning to Anesthesia After Burnout, Pain Management, ICU med or administrative job? We Built a Path Back

Burnout or time away in pain, ICU, or administration doesn’t erase your anesthesia training—it just requires a structured path back. For many physicians, it simply means you stepped away to regroup. We work with anesthesiologists every day who want to return to clinical anesthesia after time away in: administration or leadership roles pain medicine critical […]

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Anesthesiology Published - 9 April, 2026    By - Dr Clemens
Remifentanil–esketamine–based General Anesthesia Strategy for Microelectrode-guided Deep-brain Stimulation for Parkinson Disease

Authors: Huang D et al. Anesthesiology 144(4):1021–1024, April 2026 Summary:This prospective exploratory study evaluates a novel general anesthesia strategy using Remifentanil and Esketamine for deep-brain stimulation (DBS) surgery in patients with Parkinson disease. Traditionally, DBS electrode placement is performed under awake or lightly sedated conditions to preserve microelectrode recording signals, but this approach can be […]

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Anesthesiology Published - 9 April, 2026    By - Dr Clemens
Critical Closing and Tissue Perfusion Pressures in Sepsis: Implications for Risk Stratification

Authors: Wang J et al. Anesthesiology 144(4):886–897, April 2026 Summary:This large retrospective cohort study evaluates whether critical closing pressure (Pcc) and tissue perfusion pressure (TPP) provide better prognostic insight than mean arterial pressure (MAP) alone in patients with sepsis. While MAP has traditionally been the primary target for resuscitation, it does not fully capture the […]

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Anesthesiology Published - 9 April, 2026    By - Dr Clemens
Effect of Sevoflurane Concentration, Blood Pressure, Arterial Carbon Dioxide Tension, Temperature, and Stimulation on Spinal Cord Blood Flow in Patients Undergoing Spinal Surgery

Authors: Asif H et al. Anesthesiology 144(4):1012–1015, April 2026 Summary:This exploratory study examines how intraoperative variables affect spinal cord blood flow (SCBF) in humans using laser speckle contrast imaging, a technique that provides real-time, high-resolution perfusion mapping during spinal surgery. The key finding is that spinal cord blood flow behaves differently from cerebral blood flow […]

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Anesthesiology Published - 9 April, 2026    By - Dr Clemens
Minimum Alveolar Concentration Ratio Factors: Reply

Authors: Douville N et al. Anesthesiology 144(4):1026–1027, April 2026 Summary:This reply reinforces and expands on the argument that traditional hemodynamic parameters are inadequate for assessing anesthetic depth, agreeing with prior commentary that blood pressure and heart rate reflect secondary physiologic responses rather than direct brain effects. The authors emphasize that anesthetic depth should be grounded […]

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Anesthesiology Published - 9 April, 2026    By - Dr Clemens
Minimum Alveolar Concentration Ratio Factors: Comment

Authors: Muggleton E Anesthesiology 144(4):1025–1026, April 2026 Summary:This commentary challenges one of the most ingrained assumptions in anesthesiology—that hemodynamic stability reflects adequate depth of anesthesia. Building on prior research, the author argues that relying on blood pressure and heart rate as primary indicators of anesthetic depth is fundamentally flawed because these are indirect, downstream effects […]

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Anesthesiology Published - 9 April, 2026    By - Dr Clemens
Returning to Anesthesia After Burnout, Pain Management, ICU med or administrative job? We Built a Path Back

Burnout or time away in pain, ICU, or administration doesn’t erase your anesthesia training—it just requires a structured path back. For many physicians, it simply means you stepped away to regroup. We work with anesthesiologists every day who want to return to clinical anesthesia after time away in: administration or leadership roles pain medicine critical […]

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Anesthesiology Published - 8 April, 2026    By - Dr Clemens
Training the Next Generation of Anesthesiologists: A Cross-sectional Mixed-methods Study on Mentorship in Anesthesiology

Authors: Gisselbaek M et al. Anesthesiology 144(4):1008–1011, April 2026 Summary:This cross-sectional mixed-methods study examines mentorship dynamics in anesthesiology, with a particular focus on gender differences. Using a national survey of over 1,100 members of the American Society of Anesthesiologists along with focus groups, the authors explored how mentorship is accessed, structured, and experienced. The study […]

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Anesthesiology Published - 8 April, 2026    By - Dr Clemens
Management of Chronic Antihypertensive Medications in the Perioperative Period

Authors: Tang J et al. Anesthesiology 144(4):967–977, April 2026 Summary:This comprehensive review addresses the complex and often controversial management of chronic antihypertensive medications in the perioperative period. It synthesizes recent randomized trials, guidelines, and observational data to provide a practical, patient-centered framework for decision-making. A central theme is that there is no one-size-fits-all approach. For […]

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