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Authors: Sugiyama D et al. Anesthesiology 144(4):965–966, April 2026 Summary:This brief clinical report revisits retrograde intubation as a critical rescue airway technique, emphasizing its continued relevance despite the widespread adoption of video laryngoscopy. While modern airway tools have significantly improved visualization, the authors highlight that certain scenarios—such as airway tumors, severe distortion, or bleeding—can render […]
Read MoreAuthors: Riazi S et al. Anesthesiology 144(4):776–783, April 2026 Summary:This article presents a practical, North American–focused framework for evaluating patients at risk for malignant hyperthermia (MH) in the era of widespread genetic testing. As genomic testing becomes more accessible and commonly performed—even as part of routine screening—anesthesiologists are increasingly encountering patients with genetic variants associated […]
Read MoreAuthors: Jansen S et al. Anesthesiology 144(4):913–925, April 2026 Summary:This randomized, double-blind, placebo-controlled study compares the respiratory and analgesic effects of Cebranopadol with Oxycodone in healthy volunteers. Cebranopadol is a novel analgesic that activates both nociceptin (NOP) and µ-opioid (MOP) receptors, raising the possibility of effective pain control with less respiratory depression than traditional opioids. […]
Read MoreIf you are having problems staffing or managing your anesthesia department, you are not alone. Hospitals and surgery centers across the country are facing the same challenges—and they are getting worse, not better. The reality is simple: anesthesia coverage has become a make-or-break issue for operating room efficiency, surgeon satisfaction, and ultimately hospital revenue. When […]
Read MoreBurnout or time away in pain, ICU, or administration doesn’t erase your anesthesia training—it just requires a structured path back. For many physicians, it simply means you stepped away to regroup. We work with anesthesiologists every day who want to return to clinical anesthesia after time away in: administration or leadership roles pain medicine critical […]
Read MoreHardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]
Read MoreAuthors: Wang T et al. Anesthesiology 144(4):837–852, April 2026 Summary:This prospective study explores whether electroencephalogram (EEG) patterns—specifically phase–amplitude coupling (PAC)—can serve as a real-time marker of nociception and analgesic effectiveness during surgery. Traditional intraoperative monitoring of pain relies largely on indirect signs such as hemodynamics, but EEG-based measures may offer a more direct window into […]
Read MoreAuthors: Furdyna M et al. Anesthesiology 144(4):796–810, April 2026 Summary:This large multicenter retrospective cohort study provides one of the most comprehensive evaluations of maternal cardiac arrest during peripartum anesthetic care in the United States. Using data from over 778,000 deliveries across 60 institutions, the authors identified 87 cases of maternal cardiac arrest, corresponding to an […]
Read MoreAuthors: Hussain N et al. Anesthesiology 144(4):898–912, April 2026 Summary:This study evaluates the strength of evidence supporting spinal cord stimulation (SCS) for chronic pain by applying the fragility index—a statistical measure that assesses how many outcome changes would be needed to overturn a trial’s results. Unlike traditional P values, the fragility index provides insight into […]
Read MoreAuthors: Jung S et al. Anesthesiology 144(4):871–885, April 2026 Summary:This experimental study investigates a key mechanism behind anesthetic-induced neurotoxicity, focusing on how Isoflurane disrupts calcium regulation in neurons. The authors specifically examined whether impaired calcium removal—rather than increased calcium entry—drives neuronal injury. Using mouse neuronal cultures, the study demonstrated that isoflurane significantly prolongs the time […]
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