Authors: Sheoran B et al. Cureus 18(2): e104270, February 25, 2026 This prospective observational study evaluated whether adding low-dose clonidine (0.5 mcg/kg) to 0.2% ropivacaine prolongs postoperative analgesia in ultrasound-guided supraclavicular brachial plexus blocks for upper limb surgeries. Ninety adult patients were divided into two groups: ropivacaine alone (Group A, n=45) versus ropivacaine plus clonidine […]
Read MoreAuthors: Hovgaard H et al. Anesthesiology 144(4):823–836, April 2026 Summary:This randomized controlled trial examined whether extending goal-directed fluid therapy (GDFT) beyond the operating room and individualizing blood pressure targets improves outcomes after esophagectomy. Patients were randomized to either standard care or an intervention strategy that optimized cardiac output and used each patient’s baseline nighttime mean […]
Read MoreAuthors: Lei S et al. Anesthesiology 144(4):811–822, April 2026 Summary:This large observational study evaluates the clinical significance of discordance between creatinine-based and cystatin C–based estimates of renal function in surgical patients. Using two large cohorts totaling nearly 59,000 patients undergoing major noncardiac surgery, the authors examined whether differences between these two measurements (eGFRdiff) predict postoperative […]
Read MoreAuthor: Mark D. Neuman, MD, M.Sc, Editor Anesthesiology, April 2026 Summary:This study explores a novel mechanism of peripheral pain modulation through glial cell signaling. Researchers showed that a diazepam-binding inhibitor (DBI) influences mechanosensation by acting on glial cells in dorsal root ganglia. Blocking DBI reduced neuronal excitability and decreased mechanical pain hypersensitivity in animal models. […]
Read MoreAuthor: Sophie Eydis Becker’s ASC Review Anesthesiology leaders across the country are drawing national attention for achievements, innovation and career moves shaping the specialty. From a lifetime achievement honor for a pioneer in pediatric cardiac anesthesia to the launch of a telehealth ketamine therapy platform, these developments highlight the evolving influence surrounding the field. Here are […]
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