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Authors: Per Ederoth, M.D., Ph.D. et al Anesthesiology 4 2018, Vol.128, 710-717. Background: Acute kidney injury is a common complication after cardiac surgery, leading to increased morbidity and mortality. One suggested cause for acute kidney injury is extracorporeal circulation–induced ischemia–reperfusion injury. In animal studies, cyclosporine has been shown to reduce ischemia–reperfusion injury in the kidneys. We hypothesized […]
Read MoreAuthors: David O. Warner, M.D. et al Anesthesiology4 2018, Vol.128, 700-703. “The potential for adverse neurodevelopmental effects of anesthetics is clearly a complex problem and the answers are not ‘obvious’…[and] we grapple with the specific question of whether animal findings translate to children…” EXPOSURE of young animals to most clinically-utilized anesthetics in sufficient doses changes […]
Read MoreAuthors: Semler MW et al. N Engl J Med 2018 Mar 1. Acutely hospitalized patients had better outcomes with lactated Ringer’s solution than with normal saline. What is the right crystalloid for fluid resuscitation? Because limited data guide this decision, choices traditionally have been driven by culture: saline in medical units, and lactated Ringer’s solution for surgical […]
Read MoreAuthor: Jenifer Lightdale, MD, MPH A meta-analysis of 13 randomized controlled trials shows clear and consistent evidence of a decrease in respiratory compromise with capnography monitoring. Clinically significant adverse events associated with procedural sedation and analgesia (PSA)—including critical oxygen desaturation, bradycardia, hypotension and cardiac arrest—are relatively uncommon. However, their occasional occurrence should be recognized as […]
Read MoreArticle I wanted to share with our readers. BY Karen Feldscher Harvard Chan School Communications DATE March 13, 2018 A Harvard study has found that physicians’ salaries and hospital services are in part what’s behind the higher costs of U.S. health care. In 2016, the U.S. spent nearly twice as much on health care as other […]
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