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Authors: Elizabeth M. S. Lange, M.D. et al Anesthesiology 4 2018, Vol.128, 745-753 Background: Programmed intermittent boluses of local anesthetic have been shown to be superior to continuous infusions for maintenance of labor analgesia. High-rate epidural boluses increase delivery pressure at the catheter orifice and may improve drug distribution in the epidural space. We hypothesized that high-rate […]
Read MoreAuthors: Rebecca Y. Klinger, M.D., M.S. et al Anesthesiology 4 2018, Vol.128, 728-744. Background: Amyloid deposition is a potential contributor to postoperative cognitive dysfunction. The authors hypothesized that 6-week global cortical amyloid burden, determined by 18F-florbetapir positron emission tomography, would be greater in those patients manifesting cognitive dysfunction at 6 weeks postoperatively. Methods: Amyloid deposition was evaluated in cardiac […]
Read MoreAuthors: In-Kyung Song, M.D. et al Anesthesiology 4 2018, Vol.128, 718-727. Background: Pediatric cardiac patients are at risk for perioperative respiratory insufficiency. The objective of this study was to assess the utility of perioperative lung ultrasound examination in pediatric cardiac surgery. Methods: In this randomized, controlled trial, children (5 yr old or younger) undergoing cardiac surgery were allocated into […]
Read MoreThis is an article that I bet our male followers will be happy to read. Digital rectal examination (DRE) for prostate cancer screening in primary care should be discouraged given “the lack of evidence supporting its use,” according to a meta-analysis. The analysis encompassed seven studies measuring the effectiveness of DRE in screening for prostate […]
Read MoreAuthors: Deborah J. Culley, M.D. et al Anesthesiology 4 2018, Vol.128, 697-699. “…[T]here may be risk associated with exposure to general anesthesia…[but] surgery without adequate anesthesia and analgesia is simply not an option.” TWENTY-FIVE years ago, surgery was commonly performed on awake or paralyzed infants and children without the benefit of analgesics, sedatives, or anesthetics. This […]
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