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AUTHORS: Bellomy, Melissa L. MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 82-88 Background: Bleeding and venous thromboembolic disease are considered important sources of postoperative morbidity and mortality. Clinically, treatment of these 2 disorders is often competing. We sought to better understand the relative contributions of bleeding […]
Read MoreAUTHORS: Taboada, Manuel MD, PhD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 25-30 Background: In the treatment for severe acute respiratory distress syndrome (ARDS) from coronavirus disease 2019 (COVID-19), the World Health Organization (WHO) recommends prone positioning (PP) during mechanical ventilation for periods of 12–16 h/d to […]
Read MoreAUTHORS: Murphy, Glenn S. MD et al Anesthesia & Analgesia: December 10, 2020 – Volume – Issue – 10 BACKGROUND: Patients undergoing thoracoscopic procedures may be at high-risk for incomplete neuromuscular recovery and associated complications. The aim of this clinical investigation was to assess the incidence of postoperative residual neuromuscular blockade in adult thoracic surgical […]
Read MoreAUTHORS: McIsaac, Daniel I. MD, MPH, FRCPC et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10 BACKGROUND: Frailty—a multidimensional syndrome related to age- and disease-related deficits—is a key risk factor for older surgical patients. However, it is unknown which frailty instrument most accurately predicts postoperative outcomes. Our objectives were to […]
Read MoreAUTHORS: Teng, Wei-Nung MD, PhD et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10.1213/ANE.0000000000005288 BACKGROUND: Fascia blocks (eg, the transversus abdominis plane [TAP] block) target the intermuscular fascia layers. Ultrasound techniques have allowed peripheral blocks to be performed with accuracy and safety, however, with limitations. Optical coherence tomography (OCT) is […]
Read MoreAUTHORS: Jansen, Gerrit Dr med et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10. BACKGROUND: Recently, a very low incidence of 3 per 10,000 and a mortality of 30% were reported for pediatric perioperative cardiac arrest (POCA). However, high-risk patients, namely children already anesthetized on the intensive care unit (ICU), […]
Read MoreAUTHORS: Kahl, Ursula MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 420-429 BACKGROUND: Diastolic dysfunction is a risk factor for postoperative major cardiovascular events. During anesthesia, patients with diastolic dysfunction might experience impaired hemodynamic function and worsening of diastolic function, which in turn, might be associated with […]
Read MoreAUTHORS: Zhou, Yinhui MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 240-252 Background: Burn injury (BI) pain consists of inflammatory and neuropathic components and activates microglia. Nicotinic alpha 7 acetylcholine receptors (α7AChRs) expressed in microglia exhibit immunomodulatory activity during agonist stimulation. Efficacy of selective α7AChR agonist GTS-21 […]
Read MoreAUTHORS: Ortved, Milla MD et al Anesthesia & Analgesia: November 20, 2020 – Volume – Issue – 10. BACKGROUND: Diabetes increases the risk of adverse outcomes in surgical procedures, including total hip and knee arthroplasty (THA/TKA), and the prevalence of diabetic patients undergoing these procedures is high, ranging from approximately 8% to 20%. However, there […]
Read MoreAUTHORS: Varobieff, Maxime MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 556-565 BACKGROUND: Nerve damage can occur after peripheral nerve block (PNB). Ultrasound guidance does not eliminate the risk of intraneural injection or nerve injury. Combining nerve stimulation and injection pressure (IP) monitoring with ultrasound guidance has […]
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