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AUTHORS: Ortved, Milla MD et al Anesthesia & Analgesia: November 20, 2020 – Volume – Issue – 10. BACKGROUND: Diabetes increases the risk of adverse outcomes in surgical procedures, including total hip and knee arthroplasty (THA/TKA), and the prevalence of diabetic patients undergoing these procedures is high, ranging from approximately 8% to 20%. However, there […]
Read MoreAUTHORS: Varobieff, Maxime MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 556-565 BACKGROUND: Nerve damage can occur after peripheral nerve block (PNB). Ultrasound guidance does not eliminate the risk of intraneural injection or nerve injury. Combining nerve stimulation and injection pressure (IP) monitoring with ultrasound guidance has […]
Read MoreAUTHORS: Reeves, J. Jeffery MD et al Anesthesia & Analgesia: November 18, 2020 – Volume – Issue – 10. BACKGROUND: Understanding the impact of key metrics on operating room (OR) efficiency is important to optimize utilization and reduce costs, particularly in freestanding ambulatory surgery centers. The aim of this study was to assess the association […]
Read MoreAUTHORS: Lankford, Allison S. MD et al Anesthesia & Analgesia: March 2021 – Volume 132 – Issue 3 – p 777-787 BACKGROUND: The use of extracorporeal membrane oxygenation (ECMO) as a rescue therapy for cardiopulmonary failure is expanding in critical care medicine. In this case series, we describe the clinical outcomes of 21 consecutive pregnant […]
Read MoreAuthors: Anu Kewlani, M.D. et al Anesthesiology April 2021, Vol. 134, 617–625. Background The median effective dose of ropivacaine required for producing an effective costoclavicular block has not yet been determined. The authors conducted this dose-finding study with the objective of determining the median effective dose of 0.5% ropivacaine required to produce a successful costoclavicular block […]
Read MoreAuthors: L. Stan Leung, Ph.D. et al Anesthesiology April 2021, Vol. 134, 588–606. Background Cholinergic drugs are known to modulate general anesthesia, but anesthesia responses in acetylcholine-deficient mice have not been studied. It was hypothesized that mice with genetic deficiency of forebrain acetylcholine show increased anesthetic sensitivity to isoflurane and ketamine and decreased gamma-frequency brain activity. […]
Read MoreNEJM Journal Watch By the Editors The American Academy of Pediatrics has issued a list of five practices to avoid in pediatric neurologic surgery as part of the American Board of Internal Medicine’s Choosing Wisely campaign. Among them: Do not routinely perform imaging to evaluate infant head shape, as it unnecessarily exposes the child to […]
Read MoreAuthors: Glenn S. Murphy, M.D.et al Anesthesiology March 2021. Background Despite application of multimodal pain management strategies, patients undergoing spinal fusion surgery frequently report severe postoperative pain. Methadone and ketamine, which are N-methyl-d-aspartate receptor antagonists, have been documented to facilitate postoperative pain control. This study therefore tested the primary hypothesis that patients recovering from spinal fusion […]
Read MoreAuthors: Gen Li, M.Stat., M.Chem. et al Anesthesiology March 2021. Background Postoperative residual neuromuscular blockade related to nondepolarizing neuromuscular blocking agents may be associated with pulmonary complications. In this study, the authors sought to determine whether sugammadex was associated with a lower risk of postoperative pulmonary complications in comparison with neostigmine. Methods Adult patients from […]
Read MoreAuthors: Zhong-Hua Shi, M.D. et al Anesthesiology March 2021. Background The lateral abdominal wall muscles are recruited with active expiration, as may occur with high breathing effort, inspiratory muscle weakness, or pulmonary hyperinflation. The effects of critical illness and mechanical ventilation on these muscles are unknown. This study aimed to assess the reproducibility of expiratory […]
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