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Uncategorized Published - 16 April, 2021    By - Dr Clemens
Incidence, Mortality, and Characteristics of 18 Pediatric Perioperative Cardiac Arrests

AUTHORS: Jansen, Gerrit Dr med et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10.1213 BACKGROUND: Recently, a very low incidence of 3 per 10,000 and a mortality of 30% were reported for pediatric perioperative cardiac arrest (POCA). However, high-risk patients, namely children already anesthetized on the intensive care unit (ICU), were […]

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Uncategorized Published - 16 April, 2021    By - Dr Clemens
Clinical Outcomes of Pregnant and Postpartum Extracorporeal Membrane Oxygenation Patients

AUTHORS: Lankford, Allison S. MD et al Anesthesia & Analgesia: March 2021 – Volume 132 – Issue 3 – p 777-787 BACKGROUND:  The use of extracorporeal membrane oxygenation (ECMO) as a rescue therapy for cardiopulmonary failure is expanding in critical care medicine. In this case series, we describe the clinical outcomes of 21 consecutive pregnant or […]

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Uncategorized Published - 15 April, 2021    By - Dr Clemens
Association Between High Body Mass Index and Mortality Following Myocardial Injury After Noncardiac Surgery

AUTHORS: Lee, Seung-Hwa MD et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 960-968 BACKGROUND:  Despite an association between obesity and increased risks for various diseases, obesity has been paradoxically reported to correlate with improved mortality in patients with established cardiovascular disease. However, its effect has not been evaluated to […]

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Uncategorized Published - 15 April, 2021    By - Dr Clemens
Postoperative Morbidity and Mortality in Diabetic Patients After Fast-Track Hip and Knee Arthroplasty

AUTHORS: Ortved, Milla MD et al Anesthesia & Analgesia: November 20, 2020 – Volume – Issue – 10 BACKGROUND: Diabetes increases the risk of adverse outcomes in surgical procedures, including total hip and knee arthroplasty (THA/TKA), and the prevalence of diabetic patients undergoing these procedures is high, ranging from approximately 8% to 20%. However, there is […]

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Uncategorized Published - 15 April, 2021    By - Dr Clemens
Effect of Different Positions During Surgical Preparation With Combined Spinal-Epidural Anesthesia for Elective Cesarean Delivery

AUTHORS: Liu, Tianyu BSc et al Anesthesia & Analgesia: December 21, 2020 – Volume – Issue – 10 BACKGROUND: The intraoperative 15° left-tilt position during cesarean delivery has more recently been questioned regarding its effect on fetal acid-base balance and is a frequent source of complaints by surgeons. We hypothesized that a 30° left-tilt position during […]

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Uncategorized Published - 15 April, 2021    By - Dr Clemens
Efficiency Metrics at an Academic Freestanding Ambulatory Surgery Center

AUTHORS: Reeves, J. Jeffery MD et al Anesthesia & Analgesia: November 18, 2020 – Volume – Issue – 10 BACKGROUND: Understanding the impact of key metrics on operating room (OR) efficiency is important to optimize utilization and reduce costs, particularly in freestanding ambulatory surgery centers. The aim of this study was to assess the association between […]

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Uncategorized Published - 15 April, 2021    By - Dr Clemens
Pain Catastrophizing Mediates and Moderates the Link Between Acute Pain and Working Memory

DG Journal Club AUTHORS: Philip M Procento, Kevin L Rand et al. J Pain. 2021 Mar 13 The bidirectional relationship between pain and working memory (WM) deficits is well-documented but poorly understood. Pain catastrophizing – exaggerated, negative cognitive and emotional responses toward pain – may contribute to WM deficits by occupying finite, shared cognitive resources. […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
Prenatal Exposure to General Anesthesia and Childhood Behavioral Deficit

AUTHORS: Ing, Caleb MD, MS et al Anesthesia & Analgesia: January 22, 2021 – Volume – Issue – 10 BACKGROUND: Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure to anesthetic […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
A Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects

AUTHORS: Sadhasivam, Senthilkumar MD, MPH, MBA, FASA et al Anesthesia & Analgesia: January 21, 2021 – Volume – Issue – 10. BACKGROUND: Intraoperative methadone, a long-acting opioid, is increasingly used for postoperative analgesia, although the optimal methadone dosing strategy in children is still unknown. The use of a single large dose of intraoperative methadone is controversial […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
The Bitter and the Sweet: Relationship of Lactate, Glucose, and Mortality After Severe Blunt Trauma

AUTHORS: Richards, Justin E. MD et al Anesthesia & Analgesia: December 30, 2020 – Volume – Issue – 10. BACKGROUND: Hyperglycemia is associated with mortality after trauma; however, few studies have simultaneously investigated the association of depth of shock and acute hyperglycemia. We evaluated lactate, as a surrogate measure for depth of shock, and glucose levels […]

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