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Uncategorized Published - 28 April, 2021    By - Dr Clemens
Effect of Different Positions During Surgical Preparation With Combined Spinal-Epidural Anesthesia for Elective Cesarean Delivery

AUTHORS: Liu, Tianyu BSc et al Anesthesia & Analgesia: December 21, 2020 – Volume – Issue – 101213 BACKGROUND: The intraoperative 15° left-tilt position during cesarean delivery has more recently been questioned regarding its effect on fetal acid-base balance and is a frequent source of complaints by surgeons. We hypothesized that a 30° left-tilt position during […]

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Uncategorized Published - 28 April, 2021    By - Dr Clemens
Clinical Outcomes of Pregnant and Postpartum Extracorporeal Membrane Oxygenation Patients

AUTHORS: Lankford, Allison S. MD et al Anesthesia & Analgesia: March 2021 – Volume 132 – Issue 3 – p 777-787 BACKGROUND:  The use of extracorporeal membrane oxygenation (ECMO) as a rescue therapy for cardiopulmonary failure is expanding in critical care medicine. In this case series, we describe the clinical outcomes of 21 consecutive pregnant or […]

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Uncategorized Published - 28 April, 2021    By - Dr Clemens
Anatomical In Vitro Investigations of the Pediatric Larynx: A Call for Manufacturer Redesign of Tracheal Tube Cuff Location and Perhaps a Call to Reconsider the Use of Uncuffed Tracheal Tubes

AUTHORS: Isa, Malaak MD et al Anesthesia & Analgesia: April 26, 2021 – Volume – Issue – 10.1213 BACKGROUND: Some in vivo studies question the traditional “funnel-shaped” infant larynx; further anatomic examinations were warranted. Examination of fixative free fresh autopsy laryngeal and upper tracheal specimens and multiple measurements was needed to determine consistency between current tracheal […]

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Uncategorized Published - 28 April, 2021    By - Dr Clemens
Prior use of therapeutic anticoagulation does not protect against COVID-19-related clinical outcomes in hospitalised patients

DG Alerts Use of therapeutic anticoagulation prior to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was associated with a lower risk for pulmonary embolism, but not a decreased risk for other coronavirus disease 2019 (COVID-19)-related outcomes in hospitalised COVID-19 patients, including in-hospital mortality, according to a study published in the British Journal of Clinical Pharmacology. […]

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Uncategorized Published - 27 April, 2021    By - Dr Clemens
Ultrasound Evaluation of Gastric Emptying Time in Healthy Term Neonates after Formula Feeding

Authors: Jennifer J. Lee, M.D. et al  Anesthesiology April 2021. Background The current American Society of Anesthesiologists fasting guideline for formula-fed infants in the periprocedural setting is 6 h. Prolonged fasting in very young infants is associated with an increased risk for hypoglycemia and dehydration as well as patient discomfort and patient/parental dissatisfaction. This study […]

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Uncategorized Published - 27 April, 2021    By - Dr Clemens
Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain

Authors: Keith M. Vogt, M.D., Ph.D. et al  Anesthesiology April 2021. Background Despite the well-known clinical effects of midazolam and ketamine, including sedation and memory impairment, the neural mechanisms of these distinct drugs in humans are incompletely understood. The authors hypothesized that both drugs would decrease recollection memory, task-related brain activity, and long-range connectivity between […]

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Uncategorized Published - 27 April, 2021    By - Dr Clemens
Surgical Site Infections: Anesthesia Professionals Can Help Get Us on a Path to Zero

Authors: Richard C. Prielipp, MD, MBA, FCCM and David J. Birnbach, MD, MPH ASA Monitor May 2021, Vol. 85, 44–45. Approximately 2 million hospitalized patients develop health care-associated infections (HCAI) annually, contributing to over 90,000 deaths each year in the United States (J Am Coll Surg 2017;225:455-64). While the source of these infections is complex and […]

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Uncategorized Published - 27 April, 2021    By - Dr Clemens
Changes in Respiratory Muscle Thickness during Mechanical Ventilation

Authors: Zhong-Hua Shi, M.D. et al  Anesthesiology May 2021, Vol. 134, 748–759. Background The lateral abdominal wall muscles are recruited with active expiration, as may occur with high breathing effort, inspiratory muscle weakness, or pulmonary hyperinflation. The effects of critical illness and mechanical ventilation on these muscles are unknown. This study aimed to assess the reproducibility […]

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Uncategorized Published - 27 April, 2021    By - Dr Clemens
Evaluation of a Hyperbaric Oxygen Therapy Intervention in Individuals with Fibromyalgia

DG Journal Club AUTHORS: K Curtis, J Katz et al. Pain Med. 2021 Feb 16 OBJECTIVE To evaluate the feasibility and safety of hyperbaric oxygen therapy (HBOT) in patients with fibromyalgia (FM). DESIGN A cohort study with a delayed treatment arm used as a comparator. SETTING Hyperbaric Medicine Unit, Toronto General Hospital, Ontario, Canada. SUBJECTS […]

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Uncategorized Published - 26 April, 2021    By - Dr Clemens
Supplemental Intraoperative Oxygen and Long-term Mortality

Authors: Qiliang Jiang, M.D. et al Anesthesiology May 2021, Vol. 134, 709–721. Background Whether supplemental oxygen worsens long-term mortality remains unclear, with contradictory trial results. The authors therefore tested the hypothesis that supplemental oxygen (80% vs. 30%) increases the hazard for long-term mortality. Methods The authors conducted a post hoc analysis of a large multiple crossover cluster trial in […]

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