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Uncategorized Published - 1 April, 2021    By - Dr Clemens
Nonselective Compared With Selective α-Blockade Is Associated With Less Intraoperative Hypertension in Patients With Pheochromocytomas and Paragangliomas

AUTHORS: Kong, Hao MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 140-149 Background:  Both selective and nonselective α-blockade are used for preoperative preparation in patients with pheochromocytomas and paragangliomas (PPGLs). However, the effects of different types of α-blockade on perioperative outcomes remain inconclusive. This study was designed […]

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Uncategorized Published - 1 April, 2021    By - Dr Clemens
Intraoperative Cardiac Arrest During Adult Liver Transplantation: Incidence and Risk Factor Analysis From 7 Academic Centers in the United States

AUTHORS: Smith, Natalie K MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 130-139 Background:  Intraoperative cardiac arrest (ICA) has a reported frequency of 1 in 10,000 anesthetics but has a much higher estimated incidence in orthotopic liver transplantation (OLT). Single-center studies of ICA in OLT are limited […]

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Uncategorized Published - 1 April, 2021    By - Dr Clemens
Retrograde Autologous Priming in Cardiac Surgery

AUTHORS: Hensley, Nadia B. MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 100-107 Background:  Retrograde autologous priming (RAP) before cardiopulmonary bypass (CPB) may minimize allogeneic red cell transfusion. We conducted a systematic review of the literature to examine the impact of RAP on perioperative allogeneic red cell […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
The Attributable Mortality of Postoperative Bleeding Exceeds the Attributable Mortality of Postoperative Venous Thromboembolism

AUTHORS: Bellomy, Melissa L. MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 82-88 Background:  Bleeding and venous thromboembolic disease are considered important sources of postoperative morbidity and mortality. Clinically, treatment of these 2 disorders is often competing. We sought to better understand the relative contributions of bleeding […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
Effectiveness of Prone Positioning in Nonintubated Intensive Care Unit Patients With Moderate to Severe Acute Respiratory Distress Syndrome by Coronavirus Disease 2019

AUTHORS: Taboada, Manuel MD, PhD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 25-30 Background:  In the treatment for severe acute respiratory distress syndrome (ARDS) from coronavirus disease 2019 (COVID-19), the World Health Organization (WHO) recommends prone positioning (PP) during mechanical ventilation for periods of 12–16 h/d to […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
Neuromuscular and Clinical Recovery in Thoracic Surgical Patients Reversed With Neostigmine or Sugammadex

AUTHORS: Murphy, Glenn S. MD et al Anesthesia & Analgesia: December 10, 2020 – Volume – Issue – 10 BACKGROUND: Patients undergoing thoracoscopic procedures may be at high-risk for incomplete neuromuscular recovery and associated complications. The aim of this clinical investigation was to assess the incidence of postoperative residual neuromuscular blockade in adult thoracic surgical […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
A Bayesian Comparison of Frailty Instruments in Noncardiac Surgery

AUTHORS: McIsaac, Daniel I. MD, MPH, FRCPC et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10 BACKGROUND: Frailty—a multidimensional syndrome related to age- and disease-related deficits—is a key risk factor for older surgical patients. However, it is unknown which frailty instrument most accurately predicts postoperative outcomes. Our objectives were to […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
Fiber-Needle Swept-Source Optical Coherence Tomography for the Real-Time Visualization of the Transversus Abdominis Plane Block Procedure in a Swine Model

AUTHORS: Teng, Wei-Nung MD, PhD et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10.1213/ANE.0000000000005288 BACKGROUND:  Fascia blocks (eg, the transversus abdominis plane [TAP] block) target the intermuscular fascia layers. Ultrasound techniques have allowed peripheral blocks to be performed with accuracy and safety, however, with limitations. Optical coherence tomography (OCT) is […]

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Uncategorized Published - 30 March, 2021    By - Dr Clemens
Incidence, Mortality, and Characteristics of 18 Pediatric Perioperative Cardiac Arrests: An Observational Trial From 22,650 Pediatric Anesthesias

AUTHORS: Jansen, Gerrit Dr med et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10. BACKGROUND: Recently, a very low incidence of 3 per 10,000 and a mortality of 30% were reported for pediatric perioperative cardiac arrest (POCA). However, high-risk patients, namely children already anesthetized on the intensive care unit (ICU), […]

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Uncategorized Published - 30 March, 2021    By - Dr Clemens
Do Elderly Patients With Diastolic Dysfunction Require Higher Doses of Norepinephrine During General Anesthesia for Noncardiac Surgeries?

AUTHORS: Kahl, Ursula MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 420-429 BACKGROUND:  Diastolic dysfunction is a risk factor for postoperative major cardiovascular events. During anesthesia, patients with diastolic dysfunction might experience impaired hemodynamic function and worsening of diastolic function, which in turn, might be associated with […]

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