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AUTHORS: Wu, Zhijie MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 320-328 BACKGROUND: Consecutive exposure to high-dose remifentanil during anesthesia may induce remifentanil-induced postinfusion hyperalgesia (RPH). Dexmedetomidine, a highly selective α2-adrenergic receptor agonist, may have synergistic effects with opioids and aid in perioperative pain management. In this study, […]
Read MoreAUTHORS: Moon, Tiffany S. MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 308-316 BACKGROUND: Cocaine has a short biological half-life, but inactive urine metabolites may be detectable for a week following use. It is unclear if patients who test positive for cocaine but have a normal electrocardiogram and […]
Read MoreBy Alex Morrisson DG News Spinal cord stimulation using a 10 kilohertz device suppresses pain caused by diabetic neuropathy, according to a study presented at the Virtual 2021 Annual Meeting of the American Academy of Neurology (AAN). In the multicentre randomised SENZA-PDN study, patients diagnosed with diabetic neuropathy said their pain scores decreased from an […]
Read MoreDG News Having an epidural during childbirth was not associated with a greater risk of autism in the child, according to a study published in JAMA Pediatrics. “We did not find evidence for any genuine link between having an epidural and putting your baby at increased risk of autism spectrum disorder,” said senior author Alexander Butwick, […]
Read MoreDG Journal Club AUTHORS: Ira Goldsmith, Joseph George et al. J Cardiothorac Surg. 2021 Apr 13; 16(1): 78 BACKGROUND Congenital pulmonary airway malformation (CPAM) with partial anomalous pulmonary venous connection presenting as episodic retrosternal chest pain on exertion in an adult has not been described. CASE PRESENTATION A 21-year-old female, non-smoker, presented with a 4-year […]
Read MoreAuthor: Michael Walter Cardiovascular Business Researchers have found that an advanced AI model can use imaging findings to make fractional flow reserve (FFR) calculations and predict when coronary artery plaque blockages require surgery. Sharing its findings in the International Journal of Cardiology, the team noted that this algorithm could help patients avoid invasive catheterization procedures. The […]
Read MoreAuthors: Sophia Margareta Brixel, M.D. et al Anesthesiology May 2021, Vol. 134, 722–733. Background Pain management is important for ensuring early mobilization after hip arthroplasty; however, the optimal components remain controversial. Recently, the quadratus lumborum block has been proposed as an analgesic option. The current study tested the hypothesis that the posterior quadratus lumborum block […]
Read MoreDG Journal Club AUTHORS: Leanne M Aitken, Kalliopi Kydonaki et al. Thorax. 2021 Apr 15 PURPOSE To determine the effect of depth of sedation on intensive care mortality, duration of mechanical ventilation, and other clinically important outcomes. METHODS We searched MEDLINE, Embase, Cochrane Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature, […]
Read MoreAuthors: Nir Samuel, M.D., Ph.D. et al Anesthesiology May 2021, Vol. 134, 734–747. Background Anesthetics aim to prevent memory of unpleasant experiences. The amygdala and dorsal anterior cingulate cortex participate in forging emotional and valence-driven memory formation. It was hypothesized that this circuitry maintains its role under sedation. Methods Two nonhuman primates underwent aversive tone–odor […]
Read MoreDG Journal Club AUTHORS: Joan Isabelle Tankou, Olivia Foley et al. Int J Gynecol Cancer. 2021 Apr 15 OBJECTIVE The objective of this study was to determine whether the implementation of an enhanced recovery after surgery (ERAS) protocol is associated with earlier return to intended oncology treatment following interval cytoreductive surgery for advanced gynecologic cancers. […]
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