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Uncategorized Published - 12 May, 2021    By - Dr Clemens
Comparison of opioid local anesthetic combination regimens using the number of self-administrated boluses in patient-controlled epidural analgesia after cesarean section

DG Journal Club AUTHORS: Go Otao, Toyoaki Maruta et al. Medicine (Baltimore). 2021 Apr 30; 100(17): e25560 ABSTRACT The aim of this study was to assess the efficacy of combined opioids by comparing four regimens of patient-controlled epidural analgesia (PCEA) after cesarean section.Parturient patients who underwent elective or emergent cesarean section under combined spinal and […]

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Uncategorized Published - 12 May, 2021    By - Dr Clemens
Anesthetic Hypersensitivity in a Case-Controlled Series of Patients With Mitochondrial Disease

AUTHORS: Hsieh, Vincent C. MD et al Anesthesia & Analgesia: January 15, 2021 BACKGROUND: Children with mitochondrial disease undergo anesthesia for a wide array of surgical procedures. However, multiple medications used for their perioperative care can affect mitochondrial function. Defects in function of the mitochondrial electron transport chain (ETC) can lead to a profound hypersensitivity to […]

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Uncategorized Published - 12 May, 2021    By - Dr Clemens
Assisted Fluid Management Software Guidance for Intraoperative Fluid Administration

Authors: Kamal Maheshwari, M.D., M.P.H. et al  Anesthesiology April 2021 Background Excessive or inadequate fluid administration causes complications, but despite this, fluid administration during noncardiac surgery is highly variable. Goal-directed management helps optimize the amount and timing of fluid administration; however, implementation is difficult because algorithms are complex. The authors therefore tested the performance of […]

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Uncategorized Published - 11 May, 2021    By - Dr Clemens
Safety and quality of perioperative anesthesia care-Ensuring safe care for older people living with frailty

DG Journal Club Authors: Matthias Derwall, Mark Coburn Best Pract Res Clin Anaesthesiol. 2021 May; 35(1): 3-9 The clinical concept of frailty as a detectable and improvable clinical condition has emerged in the field of geriatric medicine over the past two decades. Albeit frailty can be described as the rapid deterioration of organ function during […]

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Uncategorized Published - 11 May, 2021    By - Dr Clemens
The Effect of Low-Dose Intraoperative Ketamine on Closed-Loop-Controlled General Anesthesia

AUTHORS: Napoleone, Gabby BSc et al Anesthesia & Analgesia: February 8, 2021 BACKGROUND: Closed-loop control of propofol-remifentanil anesthesia using the processed electroencephalography depth-of-hypnosis index provided by the NeuroSENSE monitor (WAVCNS) has been previously described. The purpose of this placebo-controlled study was to evaluate the performance (percentage time within ±10 units of the setpoint during the maintenance […]

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Uncategorized Published - 11 May, 2021    By - Dr Clemens
Cannabinoid Receptor-2 Activation in Keratinocytes Contributes to Elevated Peripheral β-Endorphin Levels in Patients With Obstructive Jaundice

AUTHORS: Tao, Kunming MD, PhD et al Anesthesia & Analgesia: February 8, 2021 BACKGROUND: Cholestatic diseases are often accompanied by elevated plasma levels of endogenous opioid peptides, but it is still unclear whether central or peripheral mechanisms are involved in this process, and little is known about the change of pain threshold in these patients. The […]

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Uncategorized Published - 11 May, 2021    By - Dr Clemens
How valve type and anesthesia strategy affect 1-year TAVR outcomes

Author: Michael Walter Cardiovascular Business As transcatheter aortic valve replacement (TAVR) continues to gain popularity, researchers all over the world are working to learn as much as possible about how to boost outcomes while still delivering high-quality care. One team out of Germany, for example, explored how the care team’s heart valve of choice and […]

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Uncategorized Published - 11 May, 2021    By - Dr Clemens
A Case Report from the Anesthesia Incident Reporting System

ASA Monitor October 2020, Vol. 84, 13–14. Case 2020-10: Operating in a digital vacuum An active 4-year-old girl underwent anesthesia for routine MRI evaluation of medulloblastoma at a freestanding health care facility. Multiple previous anesthetics for the same investigation were noted to be uneventful. The parental MRI screening questionnaire noted a potential past reaction to […]

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Uncategorized Published - 10 May, 2021    By - Dr Clemens
A Survey of the Society for Pediatric Anesthesia on the Use, Monitoring, and Antagonism of Neuromuscular Blockade

AUTHORS: Faulk, Debra J. MD et al Anesthesia & Analgesia: February 4, 2021 – Volume – Issue – 10.1213 BACKGROUND: Although the package insert clearly states that “the safety and efficacy of sugammadex in pediatric patients have not been established,” we hypothesized that sugammadex is used widely in pediatric anesthetic practice supplanting neostigmine as the primary […]

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Uncategorized Published - 10 May, 2021    By - Dr Clemens
Intraoperative Analgesia Reduces Postoperative Pain, Opioid Use After Ambulatory Breast Surgery

DG News Authior: Brian Hoyle Local anesthetics reduce opioid requirement and pain scores after lumpectomy and sentinel node biopsy with multimodal analgesia, according to a study presented at the 2021 Virtual Meeting of the Society of Surgical Oncology (SSO). “Multimodal analgesia during ambulatory breast surgery is associated with reduced postoperative opioid use and pain scores, […]

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