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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Perioperative Ulnar Neuropathy: A Contemporary Estimate of Incidence and Risk Factors

AUTHORS: Pulos, Bridget P. MD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1429-1437 BACKGROUND:  Retrospective and prospective studies 2 decades ago from the authors’ institution reported the incidence of perioperative ulnar neuropathy persisting for at least several months in a noncardiac adult surgical population to be between 30 […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Anesthesia for children with complete trisomy 18 (Edwards syndrome)

DG Journal Club AUTHORS: Erin E Birmingham, Astrid G Stucke et al. Paediatr Anaesth. 2021 Feb 28 BACKGROUND Trisomy 18 or Edwards syndrome is the second most common aneuploidy with a prevalence between 1/3000 and 1/10 000 live births. The syndrome encompasses malformations of the central nervous, cardiac, respiratory, gastrointestinal, and genitourinary systems. Trisomy 18 carries […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Evaluation of Drug Wastage in the Operating Rooms and Intensive Care Units of a Regional Health Service

AUTHORS: Barbariol, Federico MD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1450-1456 BACKGROUND:  Pharmacological treatments for critical processes in patients need to be initiated as rapidly as possible; for this reason, it is a standard of care to prepare the main anesthesia and emergency drugs in advance. As […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Systematic review of outcomes and endpoints in acute migraine clinical trials

DG Journal Club AUTHORS: Carrie R Houts, James S McGinley et al. Headache. 2021 Feb; 61(2): 263-275 BACKGROUND/OBJECTIVE To review the acute migraine clinical trial literature and provide a summary of the endpoints and outcomes used in such trials. METHOD A systematic literature review, following a prespecified (but unregistered) protocol developed to adhere to recommendations […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Dimethyl Fumarate Reduces Oxidative Stress and Pronociceptive Immune Responses in a Murine Model of Complex Regional Pain Syndrome

AUTHORS: Guo, Tian-Zhi MD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1475-1485 BACKGROUND:  Complex regional pain syndrome (CRPS) is a highly disabling cause of pain often precipitated by surgery or trauma to a limb. Both innate and adaptive immunological changes contribute to this syndrome. Dimethyl fumarate (DMF) works […]

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Uncategorized Published - 18 May, 2021    By - Dr Clemens
Subcostal Anterior Quadratus Lumborum Block Versus Epidural Block for Analgesia in Open Nephrectomy

AUTHORS: Elsharkawy, Hesham MD, MBA, MSc, FASA et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 1138-1145 BACKGROUND:  Epidural block are often used for analgesia after open nephrectomy surgery. Subcostal anterior quadratus lumborum block may be an alternative. We therefore tested the hypothesis that the continuous subcostal anterior quadratus lumborum […]

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Uncategorized Published - 18 May, 2021    By - Dr Clemens
Availability of Inpatient Pediatric Surgery in the United States

Authors: Michael L. McManus, M.D., M.P.H. et al Anesthesiology June 2021, Vol. 134, 852–861. Background In 2015, the American College of Surgeons began its Children’s Surgery Verification Quality Improvement Program, promulgating standards intended to promote regionalization and improve pediatric surgical care. It was hypothesized that pediatric surgical care was already highly regionalized and concentrated before […]

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Uncategorized Published - 18 May, 2021    By - Dr Clemens
Dimethyl Fumarate

AUTHORS: Yang, Chen MD et al Anesthesia & Analgesia: March 2021 BACKGROUND: Intraoperative hypothermia is a common complication after neuraxial block in cesarean delivery. At least 1 animal study has found that carbohydrate loading can maintain the body temperature of rats during general anesthesia, but it is unclear whether carbohydrate loading is beneficial for body temperature […]

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Uncategorized Published - 18 May, 2021    By - Dr Clemens
Association Between Ionized Calcium Concentrations During Hemostatic Transfusion and Calcium Treatment With Mortality in Major Trauma

AUTHORS: Chanthima, Phuriphong MD et al Anesthesia & Analgesia: March 2021 BACKGROUND: Transfusion of citrated blood products may worsen resuscitation-induced hypocalcemia and trauma outcomes, suggesting the need for protocolized early calcium replacement in major trauma. However, the dynamics of ionized calcium during hemostatic resuscitation of severe injury are not well studied. We determined the frequency of […]

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Uncategorized Published - 18 May, 2021    By - Dr Clemens
Comparison of Liposomal Bupivacaine and Conventional Local Anesthetic Agents in Regional Anesthesia

AUTHORS: Jin, Zhaosheng MBBS et al Anesthesia & Analgesia: February 2021 BACKGROUND: Pain is one of the most common adverse events after surgery. Regional anesthesia techniques are effective for pain control but have limited duration of action. Liposomal bupivacaine is a long-acting formulation of bupivacaine. We conduct this systematic review to assess whether liposomal bupivacaine may […]

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