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AUTHORS: Faulk, Debra J. MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1518-1526 BACKGROUND: Although the package insert clearly states that “the safety and efficacy of sugammadex in pediatric patients have not been established,” we hypothesized that sugammadex is used widely in pediatric anesthetic practice supplanting neostigmine as […]
Read MoreAUTHORS: Packiasabapathy, Senthil MD et al Anesthesia & Analgesia: May 2021 BACKGROUND: Safe postoperative pain relief with opioids is an unmet critical medical need in children. There is a lack of objective, noninvasive bedside tool to assess central nervous system (CNS) effects of intraoperative opioids. Proactive identification of children at risk for postoperative respiratory depression (RD) […]
Read MoreAUTHORS: Waseem, Rida MA et al Anesthesia & Analgesia: May 2021 BACKGROUND: Long-term use of opioids for treatment of chronic pain is associated with significant risks including worsening unrecognized or untreated sleep apnea that may increase morbidity and mortality. Overnight oximetry has been validated for predicting sleep apnea in surgical and sleep clinic patients. The objective […]
Read MoreAUTHORS: Blecha, Sebastian MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1677-1683 BACKGROUND: Health care and outcome of critically ill patients are marked by gender-related differences. Several studies have shown that male patients in intensive care units (ICU) more often receive mechanical ventilation, dialysis, pulmonary arterial catheterization (PAC), […]
Read MoreAuthors: Pant, Tarun PhD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1614-1625 Abstract Preclinical investigations in animal models have consistently demonstrated neurobiological changes and life-long cognitive deficits following exposure to widely used anesthetics early in life. However, the mechanisms by which these exposures affect brain function remain poorly […]
Read MoreAuthors: Subramanian, Vigneshwar BA et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1603-1613 Abstract Researchers often convert prediction tools built on statistical regression models into integer scores and risk classification systems in the name of simplicity. However, this workflow discards useful information and reduces prediction accuracy. We, therefore, investigated […]
Read MoreAuthors: Abraham, Joanna PhD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1563-1575 Abstract Intraoperative handoffs between anesthesia clinicians are critical for care continuity. However, such handoffs pose a significant threat to patient safety. This systematic review synthesizes the empirical evidence on the (a) effect of intraoperative handoffs on […]
Read MoreAuthors: Bauer, Melissa E DO et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1531-1544 Abstract Because up to 12% of obstetric patients meet criteria for the diagnosis of thrombocytopenia in pregnancy, it is not infrequent that the anesthesiologist must decide whether to proceed with a neuraxial procedure in an […]
Read MoreAUTHORS: Schober, Patrick MD, PhD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1592-1593 KEY POINT: Generalized linear mixed-effects models are a family of statistical methods to analyze a variety of nonindependent (correlated) outcome data. In this issue of Anesthesia & Analgesia, Kimura Kuroiwa et al1 report results of a randomized […]
Read MoreAUTHORS: Woodworth, Glenn E. MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1579-1591 BACKGROUND: Modern medical education requires frequent competency assessment. The Accreditation Council for Graduate Medical Education (ACGME) provides a descriptive framework of competencies and milestones but does not provide standardized instruments to assess and track trainee […]
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