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AUTHORS: Xuan, Chengluan MD, PhD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Peripheral nerve block (PNB) with perineural local anesthetic is used for anesthesia or analgesia with many benefits. To extend these benefits, various adjuvant drugs have been used to prolong the duration of analgesia. We aimed to evaluate the effectiveness of various adjuvants at […]
Read MoreAUTHORS: Verwijmeren, Lisa MD, PhD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Acute kidney injury (AKI) is associated with mortality after cardiac surgery. Novel risk factors may improve identification of patients at risk for renal injury. The authors evaluated the association between preoperative biomarkers that reflect cardiac, inflammatory, renal, and metabolic disorders and cardiac surgery–associated […]
Read MoreAuthor: Michael Walter Cardiovascular Business A new cardiac measurement obtained by wireless sensors in the pulmonary arteries could provide significant value for heart failure patients, according to a new analysis published in Heart, Lung and Circulation. This new measurement—pulmonary artery proportional pulse pressure (PAPP)—can be used to identify patients facing an especially high risk of hospitalization […]
Read MoreAUTHORS: Stundner, Ottokar MD, MBA et al Anesthesia & Analgesia: June 2021 BACKGROUND: An increasing body of evidence demonstrates an association between obstructive sleep apnea (OSA) and adverse perioperative outcomes. However, large-scale data on open colectomies are lacking. Moreover, the interaction of obesity with OSA is unknown. This study examines the impact of OSA, obesity, or […]
Read MoreAUTHORS: Lee, Allison MD, MS et al Anesthesia & Analgesia: June 2021 BACKGROUND: Cervical cerclage is a short ambulatory procedure. For spinal anesthesia, local anesthetic agents with rapid postoperative resolution are desired. We hypothesized that in combination with fentanyl, intrathecal 2-chloroprocaine would produce earlier resolution of motor block, resulting in shorter time to meet recovery room […]
Read MoreAUTHORS: Su, Lin MD, PhD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Remifentanil can induce postinfusion cold hyperalgesia. N-methyl-d-aspartate receptor (NMDAR) activation and upregulation of transient receptor potential melastatin 8 (TRPM8) membrane trafficking in dorsal root ganglion (DRG) are critical to cold hyperalgesia derived from neuropathic pain, and TRPM8 activation causes NMDAR-dependent cold response. Contribution of […]
Read MoreAuthors: Thiele, Robert H. MD et al Anesthesia & Analgesia: June 2021 Abstract While intraoperative mortality has diminished greatly over the last several decades, the risk of death within 30 days of surgery remains stubbornly high and is ultimately related to perioperative organ failure. Perioperative strokes, while rare (<2% in noncardiac surgery), are associated with a […]
Read MoreAUTHORS: Won, Dongwook MD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Cricoid pressure has been used as a component of the rapid sequence induction and intubation technique. However, concerns have been raised regarding the effectiveness and safety of cricoid pressure. Paratracheal pressure, a potential alternative to cricoid pressure to prevent regurgitation of gastric contents or […]
Read MoreAuthor: Tony Mira F1rstNews The anticipation is palpable. It’s the early 1970s and you’ve just paid a whopping $7 to hear the Who, live and in concert. The hall is full. The audience is cranked and ready to rock; but before Roger Daltrey can come on stage to sing Pinball Wizard and assure you that We […]
Read MoreDG Journal Club AUTHORS: Sujung Park, Ji-Ho Kim et al. Paediatr Anaesth. 2021 May BACKGROUND Although a neuromuscular blocking agent during induction of anesthesia is the standard of care in adults, some pediatric anaesthesiologists remain concerned about their use for several reasons. Therefore, propofol and short-acting opioids with a moderate concentration of sevoflurane have been […]
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