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ASA Monitor February 2022, Vol. 86, 20. What We’ve Got Here Is Failure to Communicate A first dose of ketorolac was given early by a different provider. After scanning the ketorolac at the end of the case, I did not confirm that any had already been administered. The error was discovered during handoff as I was […]
Read MoreAuthors: Mathieu Blot, M.D., Ph.D. et al Anesthesiology February 2022, Vol. 136, 293–313. Background Mechanical ventilation for pneumonia may contribute to lung injury due to factors that include mitochondrial dysfunction, and mesenchymal stem cells may attenuate injury. This study hypothesized that mechanical ventilation induces immune and mitochondrial dysfunction, with or without pneumococcal pneumonia, that could […]
Read MoreAUTHOR: Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C. Anesthesiology February 2022, Vol. 136, 255–257. Anesthesiologists routinely assess and provide perioperative care for patients who are older and vulnerable to adverse postoperative outcomes. For many older patients, this vulnerability can be traced back to the presence of frailty, a multidimensional syndrome related to the accumulation of age- and […]
Read MoreAUTHOR: Vinita Singh, M.D. and Steven P. Cohen, M.D. Anesthesiology February 2022, Vol. 136, 261–264. There are more than a dozen terms denoting “complex regional pain syndrome,” a condition previously known as “reflex sympathetic dystrophy.” The numerous “synonyms” reflect not only its importance in pain medicine (not unlike the linguistic lore that within Eskimo-Aleut languages, there […]
Read MoreAuthors: Tori N. Sutherland, MD, MPH et al Pediatrics April 2022 BACKGROUND: Children who undergo common outpatient surgeries are routinely prescribed opioids, although available evidence suggests opioids should be used with discretion for procedures associated with mild to moderate pain. The study assessed trends in postoperative opioid prescribing over time to determine if prescribing declined. […]
Read MoreAUTHORS: Yujia Li et al J Shoulder Elbow Surg. 2022 Apr 14 BACKGROUND Total shoulder arthroplasties and rotator-cuff repair surgeries result in considerable postoperative pain. Optimal postoperative pain management based on a multidisciplinary approach are necessary to promote early postoperative rehabilitation. The purpose of this study was to compare liposomal bupivacaine (LB) to traditional, non-liposomal […]
Read MoreAuthors: Thomas Riva, M.D. et al Anesthesiology January 2022, Vol. 136, 82–92. Background Anesthesia studies using high-flow, humidified, heated oxygen delivered via nasal cannulas at flow rates of more than 50 l · min–1 postulated a ventilatory effect because carbon dioxide increased at lower levels as reported earlier. This study investigated the increase of arterial partial pressure of […]
Read MoreAuthor: Tony Mira F1rstNews Summary The prevalence of opioid usage among America’s patients has generated the need for a set of protocols to be used by those providing acute pain care. A consortium of 15 medical societies has recently provided best-practice recommendations. The second law of thermodynamics, which is an axiom of accepted science, says […]
Read MoreAUTHORS: Fassbender, Philipp MD et al Anesthesia & Analgesia: April 2022 – Volume 134 – Issue 4 – p 858-868 BACKGROUND: The G-protein–coupled receptor kinase 5 (GRK5) is a mediator of cardiovascular homeostasis and participates in inflammation and cardiac fibrosis, both being involved in the development of diastolic dysfunction (DD). While mechanisms of transcriptional regulation of […]
Read MoreAuthors: Cara Hughes and Andreas Klein #TheAnesthesia Blog For many, the COVID-19 pandemic brought the stark reality of our mortality into focus. Along with the controversial application of ‘blanket’ DNACPR orders, it has forced all in the profession to consider how we involve our patients in the difficult conversations and decisions regarding end-of-life care. The […]
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