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Authors: Mathieu Blot, M.D., Ph.D. et al Anesthesiology February 2022, Vol. 136, 293–313. Background Mechanical ventilation for pneumonia may contribute to lung injury due to factors that include mitochondrial dysfunction, and mesenchymal stem cells may attenuate injury. This study hypothesized that mechanical ventilation induces immune and mitochondrial dysfunction, with or without pneumococcal pneumonia, that could […]
Read MoreAuthors: Ricardo Alvarez-Jimenez, M.D., Ph.D. et al Anesthesiology February 2022, Vol. 136, 279–292. Background Numerous pharmacokinetic models have been published aiming at more accurate and safer dosing of dexmedetomidine. The vast majority of the developed models underpredict the measured plasma concentrations with respect to the target concentration, especially at plasma concentrations higher than those used […]
Read MoreAuthors: David H. Kim, M.D. et al Anesthesiology March 2022, Vol. 136, 434–447. Background The interscalene nerve block provides analgesia for shoulder surgery. To extend block duration, provide adequate analgesia, and minimize opioid consumption, the use of adjuvants such as dexamethasone as well as the application of perineural liposomal bupivacaine have been proposed. This randomized, […]
Read MoreAuthors: Leopoldo V. Rodriguez, MD, MBA, FAAP, FASA, SAMBA-F et al ASA Monitor September 2021, Vol. 85, 25–26. There are over 5,800 Centers for Medicare & Medicaid Services (CMS)-certified ambulatory surgery centers (ASCs) in the United States, which are located in every state, each of which has its own laws and rules that govern ambulatory surgery […]
Read MoreAuthors: Michael A. Gropper, MD, PhD ASA Monitor October 2021, Vol. 85, 21–23. While it is impossible to predict the future of anesthesiology, we can learn much from current trends in perioperative care. Advances in technology are only part of the future. Perhaps more important than technology has been the recognition that all of our […]
Read MoreAuthors: Caleb Ing, M.D., M.S. et al Anesthesiology March 2022, Vol. 136, 500–512. Anesthetic agents disrupt neurodevelopment in animal models, but evidence in humans is mixed. The morphologic and behavioral changes observed across many species predicted that deficits should be seen in humans, but identifying a phenotype of injury in children has been challenging. It […]
Read MoreEdited by Berenstain Laura K. and Spaeth James P. . Cambridge University Press 2021 Pages: 409. ISBN-13: 978-1-108-49416-8. Anesthesiology March 2022, Vol. 136, 522–523. The world of Pediatric Cardiology and Cardiac Surgery is filled with all manner of nonintuitive acronyms and eponyms: Ebstein’s Anomaly, Fontans of various sorts, Glenns, MBTS (Modified Blalock-Taussig Shunts), Mee shunts, […]
Read MoreAuthors: James W. Ibinson, MD, PhD and Daniel J. Cole, MD, FASA ASA Monitor January 2022, Vol. 86, 1–4. Aducanumab is a IgG1 monoclonal antibody therapy that targets amyloid beta (Aβ), aiding in clearance of the Aβ plaques that are a defining molecular feature of Alzheimer’s Disease (AD). Controversy erupted in June 2021 when the FDA […]
Read MoreAuthors: Cecilia Canales, M.D., M.P.H. et al Anesthesiology February 2022, Vol. 136, 268–278. Background Frailty is increasingly being recognized as a public health issue, straining healthcare resources and increasing costs to care for these patients. Frailty is the decline in physical and cognitive reserves leading to increased vulnerability to stressors such as surgery or disease […]
Read MoreAuthor: M. Anthony Cometa, M.D. Anesthesiology March 2022, Vol. 136, 517. To the Editor: The recent article by Epaud et al.1 reinforces the need for anesthesiologists to be comfortable with the flexible fiberoptic intubation technique. I read with great concern that a neurologic injury occurred because of the choice of videolaryngoscopy as the intubation approach because the […]
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