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Uncategorized Published - 10 June, 2022    By - Dr Clemens
Inflammatory Responses to Surgery and Postoperative Atrial Fibrillation

Authors: Sergey Karamnov, M.D.; Jochen D. Muehlschlegel, M.D., M.M.Sc., M.B.A. Anesthesiology June 2022, Vol. 136, 877–879. “…postoperative atrial fibrillation is not a transient benign phenomenon but rather an ominous postoperative complication associated with increased risk of thromboembolism, stroke, and mortality.” Postoperative atrial fibrillation is one of the most common complications after thoracic noncardiac surgery. Despite contemporary prevention […]

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Uncategorized Published - 10 June, 2022    By - Dr Clemens
The Importance of Branding and Rebranding – If No One Knows Who You Are and What You Are Doing, You’re Not Doing Anything

Authors: Keya A. Locke, MD, MBA; Antonio Hernandez Conte, MD, MBA, FASA ASA Monitor May 2022, Vol. 86, 25–26. During the past few years, the COVID-19 pandemic has forced us to re-evaluate many components of our work as anesthesiologists and the organizations in which we work. Part of this organizational reflection has been to identify key features […]

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Uncategorized Published - 10 June, 2022    By - Dr Clemens
Self-reported Race/Ethnicity and Intraoperative Occult Hypoxemia

Authors: Garrett W. Burnett, M.D. et al  Anesthesiology May 2022, Vol. 136, 688–696. Background Pulse oximetry is ubiquitous in anesthesia and is generally a reliable noninvasive measure of arterial oxygen saturation. Concerns regarding the impact of skin pigmentation and race/ethnicity on the accuracy of pulse oximeter accuracy exist. The authors hypothesized a greater prevalence of occult […]

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Uncategorized Published - 10 June, 2022    By - Dr Clemens
Quality of Labor Analgesia with Dural Puncture Epidural versus Standard Epidural Technique in Obese Parturients

Authors: Hon Sen Tan, M.D., M.Med., M.H.Sc. et al  Anesthesiology May 2022, Vol. 136, 678–687. Background The dural puncture epidural technique may improve analgesia quality by confirming midline placement and increasing intrathecal translocation of epidural medications. This would be advantageous in obese parturients with increased risk of block failure. This study hypothesizes that quality of labor […]

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Uncategorized Published - 10 June, 2022    By - Dr Clemens
55 IV Therapy Tips and Tricks: How to Hit the Vein in One Shot

Author: Matt Vera BS RN A lot of factors may affect the way you insert an intravenous catheter, but you have to control them and bend them to your convenience. Never rush on any nursing skills that you still not have, or take a shortcut just to achieve your goals. Along with these intravenous therapy […]

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Uncategorized Published - 9 June, 2022    By - Dr Clemens
Gas phase diffusion does not limit lung volatile anesthetic uptake rate

Author: Philip J Peyton, MD PhD MBBS FANZCA. Anesthesiology May 2022. Background Inefficiency of lung gas exchange during general anesthesia is reflected in alveolar (end tidal) to arterial (ET-arterial) partial pressure gradients for inhaled gases resulting in an increase in alveolar deadspace. Ventilation-perfusion mismatch is the main contributor to this, but it is unclear what […]

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Uncategorized Published - 9 June, 2022    By - Dr Clemens
Isoflurane Disrupts Postsynaptic Density-95 Protein Interactions Causing Neuronal Synapse Loss and Cognitive Impairment in Juvenile Mice Via Canonical Nitric Oxide Mediated Protein Kinase-G Signaling

Authors: Swati Agarwal, Ph.D. et al  Anesthesiology May 2022. Background Inhalational anesthetics are known to disrupt PDZ2 domain-mediated protein-protein interactions of the postsynaptic density (PSD)-95 protein. The aim of this study is to investigate the underlying mechanisms in response to early isoflurane exposure on synaptic PSD-95 PDZ2 domain disruption that altered spine densities and cognitive […]

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Uncategorized Published - 9 June, 2022    By - Dr Clemens
Expert Consensus Regarding Core Outcomes for Enhanced Recovery after Cesarean Delivery Studies

Authors: Pervez Sultan, M.B.Ch.B. et al  Anesthesiology Newly Published on June 2022. Background Heterogeneity among reported outcomes from enhanced recovery after cesarean delivery impact studies is high. This study aimed to develop a standardized enhanced recovery core outcome set for use in future enhanced recovery after cesarean delivery studies. Methods An international consensus study involving physicians, […]

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Uncategorized Published - 9 June, 2022    By - Dr Clemens
Early Restrictive Fluid Strategy Impairs the Diaphragm Force in Lambs with Acute Respiratory Distress Syndrome

Authors: Marloes M. Ijland, M.D. et al  Anesthesiology May 2022, Vol. 136, 749–762. Background The effect of fluid management strategies in critical illness–associated diaphragm weakness are unknown. This study hypothesized that a liberal fluid strategy induces diaphragm muscle fiber edema, leading to reduction in diaphragmatic force generation in the early phase of experimental pediatric acute respiratory […]

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Uncategorized Published - 9 June, 2022    By - Dr Clemens
Ketamine Psychedelic and Antinociceptive Effects Are Connected

Authors: Erik Olofsen, Ph.D. et al  Anesthesiology May 2022, Vol. 136, 792–801. Background Ketamine produces potent analgesia combined with psychedelic effects. It has been suggested that these two effects are associated and possibly that analgesia is generated by ketamine-induced dissociation. The authors performed a post hoc analysis of previously published data to quantify the pharmacodynamic properties of ketamine-induced […]

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