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Authors: Sharon C. Reale, M.D. et al Anesthesiology May 2022, Vol. 136, 697–708. Background Estimates for the incidence of difficult intubation in the obstetric population vary widely, although previous studies reporting rates of difficult intubation in obstetrics are older and limited by smaller samples. The goals of this study were to provide a contemporary estimate of […]
Read MoreAuthors: Nicolas Nesseler, M.D., Ph.D. et al Anesthesiology May 2022, Vol. 136, 732–748. Background Despite expanding use, knowledge on extracorporeal membrane oxygenation support during the COVID-19 pandemic remains limited. The objective was to report characteristics, management, and outcomes of patients receiving extracorporeal membrane oxygenation with a diagnosis of COVID-19 in France and to identify pre-extracorporeal membrane […]
Read MoreCardiac anesthesiologist blog Furosemide, Bumetanide Loop diuretics (carboxylic acid derivatives) are used in severe heart failure to reduce peripheral and pulmonary oedema. They are also used in chronic and acute renal failure. Mechanism of Action Loop diuretics inhibit Na+ and Cl− reabsorption in the thick ascending limb of the loop of Henle and to […]
Read MoreCardiac Anesthesiologist blog Milrinone, an analogue of amrinone, is a bipyridine derivative with inotropic activity that is almost 20 times more potent than that of amrinone and a shorter half-life. Milrinone is an effective inodilator for patients with decompensated HF and low CO after cardiac surgical procedures. Suggested administration of milrinone is a loading dose […]
Read MoreAuthors: Peter Santer, M.D., D.Phil. et al Anesthesiology July 2022, Vol. 137, 41–54. Background Mechanical power during ventilation estimates the energy delivered to the respiratory system through integrating inspiratory pressures, tidal volume, and respiratory rate into a single value. It has been linked to lung injury and mortality in the acute respiratory distress syndrome, but little […]
Read MoreAuthor: Ellen M. Soffin, M.D., Ph.D. Anesthesiology June 2022, Vol. 136, 883–884. “[This is] the best evidence to date to support bolus-based regimens for popliteal–sciatic catheters after foot and ankle surgery.” Continuous peripheral catheters provide prolonged analgesia, reduce opioid consumption, and enhance patient satisfaction after painful surgeries. Although these clinical benefits have been firmly established, the […]
Read MoreAuthors: Bi L. Li, M.D. et al Anesthesiology June 2022. Background Intranasal dexmedetomidine provides noninvasive, effective procedural sedation for pediatric patients, and has been widely used in clinical practice. However, the dosage applied has varied fourfold in pediatric clinical studies. To validate an appropriate dosing regimen, this study investigated the pharmacokinetics of intranasal dexmedetomidine in Chinese […]
Read MoreAuthors: Naveen Vanga, M.D. et al Anesthesiology July 2022, Vol. 137, 114–116. The supraglottic airway has proven its versatility in the operating room emergency room, and field resuscitation. However, the risk of pulmonary aspiration associated with supraglottic airways still exists. The fundamental design of the supraglottic airway has not been significantly changed since its inauguration in the 1980s. Second-generation supraglottic […]
Read MoreAuthors: Ian Yuan, M.D. et al Anesthesiology June 2022. Background Intraoperative isoelectric electroencephalography (EEG) has been associated with hypotension and postoperative delirium in adults. This international prospective observational study sought to determine the prevalence of isoelectric EEG in young children during anesthesia. The authors hypothesized that the prevalence of isoelectric events would be common worldwide […]
Read MoreAuthors: Romein W. G. Dujardin, M.D. et al Anesthesiology June 2022. Background Viscoelastic hemostatic assays such as rotational thromboelastometry (ROTEM) are used to guide treatment of trauma induced coagulopathy. The authors hypothesized that ROTEM derangements reflect specific coagulation factor deficiencies after trauma. Methods This was a secondary analysis of a prospective cohort study in six […]
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