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Uncategorized Published - 14 June, 2022    By - Dr Clemens
Milrinone

Cardiac Anesthesiologist blog Milrinone, an analogue of amrinone, is a bipyridine derivative with inotropic activity that is almost 20 times more potent than that of amrinone and a shorter half-life. Milrinone is an effective inodilator for patients with decompensated HF and low CO after cardiac surgical procedures. Suggested administration of milrinone is a loading dose […]

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Uncategorized Published - 13 June, 2022    By - Dr Clemens
Mechanical Power during General Anesthesia and Postoperative Respiratory Failure

Authors: Peter Santer, M.D., D.Phil. et al  Anesthesiology July 2022, Vol. 137, 41–54. Background Mechanical power during ventilation estimates the energy delivered to the respiratory system through integrating inspiratory pressures, tidal volume, and respiratory rate into a single value. It has been linked to lung injury and mortality in the acute respiratory distress syndrome, but little […]

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Uncategorized Published - 13 June, 2022    By - Dr Clemens
Optimizing Postoperative Analgesia in the Multiverse of Peripheral Nerve Catheters

Author: Ellen M. Soffin, M.D., Ph.D. Anesthesiology June 2022, Vol. 136, 883–884. “[This is] the best evidence to date to support bolus-based regimens for popliteal–sciatic catheters after foot and ankle surgery.” Continuous peripheral catheters provide prolonged analgesia, reduce opioid consumption, and enhance patient satisfaction after painful surgeries. Although these clinical benefits have been firmly established, the […]

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Uncategorized Published - 13 June, 2022    By - Dr Clemens
Population Pharmacokinetics of Intranasal Dexmedetomidine in Infants and Young Children

Authors: Bi L. Li, M.D. et al  Anesthesiology June 2022. Background Intranasal dexmedetomidine provides noninvasive, effective procedural sedation for pediatric patients, and has been widely used in clinical practice. However, the dosage applied has varied fourfold in pediatric clinical studies. To validate an appropriate dosing regimen, this study investigated the pharmacokinetics of intranasal dexmedetomidine in Chinese […]

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Uncategorized Published - 13 June, 2022    By - Dr Clemens
Moving the Gas-sampling Line Insertion Site to the Pharynx Reduces Aspiration Associated with a Supraglottic Airway

Authors: Naveen Vanga, M.D. et al  Anesthesiology July 2022, Vol. 137, 114–116. The supraglottic airway has proven its versatility in the operating room  emergency room, and field resuscitation.  However, the risk of pulmonary aspiration associated with supraglottic airways still exists.  The fundamental design of the supraglottic airway has not been significantly changed since its inauguration in the 1980s.  Second-generation supraglottic […]

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Uncategorized Published - 13 June, 2022    By - Dr Clemens
Isoelectric Electroencephalography in Infants and Toddlers during Anesthesia for Surgery: An International Observational Study

Authors: Ian Yuan, M.D. et al  Anesthesiology June 2022. Background Intraoperative isoelectric electroencephalography (EEG) has been associated with hypotension and postoperative delirium in adults. This international prospective observational study sought to determine the prevalence of isoelectric EEG in young children during anesthesia. The authors hypothesized that the prevalence of isoelectric events would be common worldwide […]

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Uncategorized Published - 11 June, 2022    By - Dr Clemens
Coagulopathy Underlying Rotational Thromboelastometry Derangements in Trauma Patients

Authors: Romein W. G. Dujardin, M.D. et al  Anesthesiology June 2022. Background Viscoelastic hemostatic assays such as rotational thromboelastometry (ROTEM) are used to guide treatment of trauma induced coagulopathy. The authors hypothesized that ROTEM derangements reflect specific coagulation factor deficiencies after trauma. Methods This was a secondary analysis of a prospective cohort study in six […]

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Uncategorized Published - 10 June, 2022    By - Dr Clemens
Inflammatory Responses to Surgery and Postoperative Atrial Fibrillation

Authors: Sergey Karamnov, M.D.; Jochen D. Muehlschlegel, M.D., M.M.Sc., M.B.A. Anesthesiology June 2022, Vol. 136, 877–879. “…postoperative atrial fibrillation is not a transient benign phenomenon but rather an ominous postoperative complication associated with increased risk of thromboembolism, stroke, and mortality.” Postoperative atrial fibrillation is one of the most common complications after thoracic noncardiac surgery. Despite contemporary prevention […]

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Uncategorized Published - 10 June, 2022    By - Dr Clemens
The Importance of Branding and Rebranding – If No One Knows Who You Are and What You Are Doing, You’re Not Doing Anything

Authors: Keya A. Locke, MD, MBA; Antonio Hernandez Conte, MD, MBA, FASA ASA Monitor May 2022, Vol. 86, 25–26. During the past few years, the COVID-19 pandemic has forced us to re-evaluate many components of our work as anesthesiologists and the organizations in which we work. Part of this organizational reflection has been to identify key features […]

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Uncategorized Published - 10 June, 2022    By - Dr Clemens
Self-reported Race/Ethnicity and Intraoperative Occult Hypoxemia

Authors: Garrett W. Burnett, M.D. et al  Anesthesiology May 2022, Vol. 136, 688–696. Background Pulse oximetry is ubiquitous in anesthesia and is generally a reliable noninvasive measure of arterial oxygen saturation. Concerns regarding the impact of skin pigmentation and race/ethnicity on the accuracy of pulse oximeter accuracy exist. The authors hypothesized a greater prevalence of occult […]

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