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Uncategorized Published - 31 May, 2023    By - Dr Clemens
Layering Migraine Medications Leads to More Effective Relief 2023

Author: Doheny K Pract Pain Manag. 2023 May/June;22(3). With additional medications now FDA-approved and available, combination therapy promises to give more patients improved outcomes. It’s an old concept in migraine management that’s been given a new name in recent years: layering. “Conceptually, it’s nothing new,” said Jay Joshi, MD, DABA, DABA-PM, FABA-PM, CEO and medical […]

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Uncategorized Published - 31 May, 2023    By - Dr Clemens
Late-Onset PsA May Increase Risk for Cardiovascular Events 2023

Author: Avery Hurt Practical Pain Management May/June 2023 Retrospective study findings may urge clinicians to consider cardiac risk factors when evaluating and treating older adults with psoriatic arthritis. Psoriatic arthritis is a complex disease with many clinical manifestations and variations that can develop over its course. In addition to the common effects on the skin, […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Motor Vehicle Crash Risk among Adults Undergoing General Surgery 2023

Authors: Timothy G. Gaulton, M.D., M.Sc. et al  Anesthesiology June 2023, Vol. 138, 602–610. Background Surgery causes transient impairment in cognition and function, which may impact driving safety. The authors hypothesized that the risk of a motor vehicle crash would increase after compared to before surgery. Methods The authors performed a nested case-crossover study within population-based […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Layering Migraine Medications Leads to More Effective Relief 2023

Author: Doheny K. Pract Pain Manag. 2023 May/June;22(3). With additional medications now FDA-approved and available, combination therapy promises to give more patients improved outcomes. It’s an old concept in migraine management that’s been given a new name in recent years: layering. “Conceptually, it’s nothing new,” said Jay Joshi, MD, DABA, DABA-PM, FABA-PM, CEO and medical […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Prevalence and Risk Factors for Chronic Post-Surgical Pain Following Cardiac Surgery 2023

Authors: Maggie ZX Xiao, BSc et al  Anesthesiology May 2023. Background Chronic post-surgical pain is a common complication of surgery. The role of psychological risk factors like depression and anxiety is substantially understudied in cardiac surgery. This study sought to identify perioperative factors associated with chronic pain at 3, 6, and 12 months after cardiac […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Deep Isoflurane Anesthesia Is Associated with Alterations in Ion Homeostasis and Specific Na+/K+-ATPase Impairment in the Rat Brain 2023

Authors: Clemens Reiffurth, Ph.D. et al  Anesthesiology June 2023, Vol. 138, 611–623. Background Maintenance of ion homeostasis is essential for normal brain function. Inhalational anesthetics are known to act on various receptors, but their effects on ion homeostatic systems, such as sodium/potassium-adenosine triphosphatase (Na+/K+-ATPase), remain largely unexplored. Based on reports demonstrating global network activity and wakefulness […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Chronic Pain at the Pharmacy: Methadone Initiation for CRPS and Comorbidities

Author: Amarquaye W. Pract Pain Manag. 2023 May/June;23(3). When a patient asks about beginning methadone therapy for CRPS, clinical pharmacist William Amarquaye advises on administration, titration, side effects, and interactions. Patient Scenario: Patient Prescribed Methadone for CRPS The Patient Patient Bob* called our pharmacy inquiring about a new prescription for methadone that he was placed […]

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Uncategorized Published - 29 May, 2023    By - Dr Clemens
Happy Memorial Day

Happy Memorial Day! May we never forget those who made the ultimate sacrifice for our freedom. Enjoy the day with your loved ones, and don’t forget to think about those who served and sacrificed. Happy Memorial Day!

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Attributable perioperative cost of frailty after major, elective non-cardiac surgery 2023

Authors: Ryan McGinn, MD MSc et al  Anesthesiology May 2023. Background Patients with frailty consistently experience higher rates of perioperative morbidity and mortality; however, costs attributable to frailty remain poorly defined. We sought to identify older patients with and without frailty using a validated, multidimensional frailty index and estimated the attributable costs in the year […]

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Assessing Potentially Modifiable Factors Associated with the Development of Postoperative Delirium

Authors: Jeanna D. Blitz, MD, FASA et al  ASA Monitor March 2023, Vol. 87, 27–28. Brain health is inextricably linked with overall physical health. Evidence for the mind-body connection and the bi-directional relationship between them continues to emerge. The past decade has also seen the emergence of a focus on multifactorial quality and outcomes metrics within […]

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