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Anesthesiology May 2024, Vol. 140, A13–A15. Trial of selective early treatment of patent ductus arteriosus with ibuprofen. N Engl J Med 2024; 390:314–25. PMID: 38265644. Article Selection: Martin J. London, M.D. Image: Adobe Stock. The presence of patent ductus arteriosus in preterm infants beyond 3 days of age, particularly 1.5 mm or larger in diameter, is associated […]
Read MoreAnesthesiology May 2024, Vol. 140, A13–A15. Transcatheter aortic-valve replacement in low-risk patients at five years. N Engl J Med 2023; 389:1949–60. PMID: 37874020. Article Selection: Martin J. London, M.D. Image: Adobe Stock. An industry-sponsored randomized study of outcome of transcatheter aortic valve replacement (TAVR) versus surgical replacement (Edwards Lifesciences PARTNER trial; SAPIEN-3 valve) in patients with severe, symptomatic […]
Read MoreAuthors: Thomas Payne, M.D. et al Anesthesiology May 2024, Vol. 140, 884–886. “[Is] delirium causative of cognitive impairment, or is it a symptom of a ‘vulnerable’ brain that was already in decline?” Although the earliest descriptions of delirium date back to 500 BC, it was the English doctor Philip Barrough who first reported in 1583 a […]
Read MoreAuthors: Anahi Perlas, M.D., F.R.C.P.C. et al Anesthesiology May 2024, Vol. 140, 991–1001. Background Pulmonary aspiration of gastric content is a serious anesthetic complication. Gastric point-of-care ultrasound can determine the type and volume of gastric content when clinical information is equivocal. However, a cutoff value of either antral cross-sectional area or volume that may be considered […]
Read MoreAuthors: Anthony Tucker-Bartley, M.D. et al Anesthesiology May 2024, Vol. 140, 1018–1019. We demonstrate a large chest wall hematoma involving the serratus anterior muscle with an extension between the pectoralis major and minor muscles. The images (fig. 1, A–D) are noncontrast chest computed tomography scans in the axial and coronal planes, showing the hematoma, noted 1 […]
Read MoreAuthors: Céline Khalifa, M.D. et al Anesthesiology May 2024, Vol. 140, 950–962. Background Impaired cognition is a major predisposing factor for postoperative delirium, but it is not systematically assessed. Anesthesia and surgery may cause postoperative delirium by affecting brain integrity. Neurofilament light in serum reflects axonal injury. Studies evaluating the perioperative course of neurofilament light in […]
Read MoreAuthors: Marie Pollak, M.D. et al Anesthesiology May 2024, Vol. 140, 979–989. Background Postoperative delirium is a common complication in elderly patients undergoing anesthesia. Even though it is increasingly recognized as an important health issue, the early detection of patients at risk for postoperative delirium remains a challenge. This study aims to identify predictors of postoperative […]
Read MoreAuthors: Melody Reese, Ph.D. et al Anesthesiology May 2024, Vol. 140, 963–978. Background Anesthesia and/or surgery accelerate Alzheimer’s disease pathology and cause memory deficits in animal models, yet there is a lack of prospective data comparing cerebrospinal fluid (CSF) Alzheimer’s disease–related biomarker and cognitive trajectories in older adults who underwent surgery versus those who have not. Thus, the […]
Read MoreAuthor: Michael R. Fettiplace, M.D., Ph.D. Anesthesiology May 2024, Vol. 140, 868–870. “[As] evidence accumulates, we find that the biologic plausibility of liposomal bupivacaine does not translate into clinical relevance.” For over a century, anesthesiologists have sought to extend the utility, duration, and safety of local anesthetics, from the original topical instillation of cocaine onto the […]
Read MoreAnesthesiology May 2024, Vol. 140, A13–A15. Cortical regulation of helping behaviour towards others in pain. Nature 2024; 626:136–44. PMID: 38267578. Article Selection: Cyril Rivat, Ph.D. Image: Adobe Stock. Prosocial behaviors are pivotal for promoting survival and social cohesion among animals. Injury triggers instinctive responses alleviating pain and reducing infection risks through behaviors like licking. In social […]
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