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Published in Br J Anaesth. 2015 Mar;114(3):384-95 Authors: Martinez V et al The role for tramadol in multimodal postsurgical analgesic strategies remains unclear. We undertook a systematic review to evaluate the utility of combining tramadol with morphine after surgery. We searched the MEDLINE, EMBASE, LILAC, Cochrane, and Clinical Trial Register databases for randomized, controlled studies […]
Read MorePublished in Clin J Pain. 2015 Jan;31(1):86-93 Authors: De Oliveira GS Jr et al OBJECTIVES: The effect of a single-dose systemic acetaminophen to treat postoperative pain has been previously quantified, but the effect of systemic acetaminophen to prevent postoperative pain is currently not well defined. The preventive analgesic effect of acetaminophen has yet to be […]
Read MorePublished in Br J Anaesth. 2015 Apr;114(4):640-5 Authors: Szental JA et al BACKGROUND: Laparoscopic cholecystectomy frequently results in significant immediate postoperative pain. A new pain monitor, analgesic nociception index (ANI(®)), based on heart rate variability, has recently been approved for intraoperative nociception monitoring. We designed a single-blind, parallel-group, randomized control trial to test the hypothesis […]
Read MorePublished in Br J Anaesth. 2015 Apr;114(4):634-9 Authors: Zou ZY et al BACKGROUND: To investigate the effects of different target plasma remifentanil concentrations on the minimum alveolar concentration of sevoflurane (MAC) for blocking adrenergic response (BAR) during laparoscopic gynaecological surgery with carbon dioxide insufflation. METHODS: Seventy-five gynaecological patients with ASA I-II undergoing laparoscopic surgery were […]
Read MorePublished in J Obstet Gynaecol. 2014 Dec 29:1-4 Authors: Genc M et al In this study we aimed to explore the effects of epidural analgesia achieved by a combination of low-dose bupivacaine and fentanyl infused through an epidural catheter on mother, foetus and labour process in nulliparous at-term pregnant women during vaginal delivery. This study […]
Read MorePatients with fibromyalgia can safely be treated with the anticonvulsant drug pregabalin (Lyrica, Pfizer Inc) for their pain while at the same time being treated for depression, a new study shows. Results of a double-blind study showed that pregabalin significantly improved mean pain scores compared with placebo in patients with fibromyalgia taking a selective serotonin […]
Read MoreConcerns over addiction and drug abuse are causing some primary care physicians (PCPs) to prescribe fewer opioids for chronic pain, according to a recent national survey on prescription drug abuse. The clinical use of prescription opioids for treating chronic pain nearly doubled from 2000 to 2010, along with an increase in opioid abuse, addiction, injury […]
Read MoreThe FDA has approved Hospira, Inc.’s Dyloject (diclofenac sodium) Injection. The proprietary nonsteroidal anti-inflammatory drug (NSAID) is indicated for the treatment of adults with mild to moderate pain and for the management of moderate to severe pain alone or in combination with opioid analgesics. “While not a replacement for opioids, Dyloject is [an] injectable therapy […]
Read MoreA review of more than 5,000 patient records has concluded that women undergoing preterm cesarean delivery have a significantly higher risk for failed spinal anesthesia than women undergoing the procedure at full term. These findings, reported by a Duke University research team suggest that an increased spinal dose—or combined spinal–epidural technique—may be necessary to reliably […]
Read MorePublished in Respir Care. 2015 Apr;60(4):567-76 Authors: Sazak H et al BACKGROUND: Transbronchial needle aspiration using endobronchial ultrasonography (EBUS-TBNA), a new minimally invasive diagnostic procedure, has been used to evaluate intrathoracic lymph nodes. It has been reported that EBUS-TBNA can be performed safely under sedation and provides a high level of patient satisfaction. We aimed […]
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