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Although 15 years have passed since the last airway injury analysis of the American Society for Anesthesiologists (ASA) Closed Claims Project, new research reveals that pharyngeal and esophageal perforations continue to be a significant source of patient morbidity and mortality—as well as liability for anesthesiologists. The investigators noted, however, that practitioner diligence is key to […]
Read MorePublished in Acta Anaestesiol Scand 2015 Apr;59(4):414-26 Authors: Heesen M et al BACKGROUND: Intravenous ketamine has been used during general and regional anaesthesia for caesarean section. No systematic review and meta-analysis on the desired effects and adverse effects of ketamine administration during caesarean section have yet been performed. METHODS: After a systematic literature search a meta-analysis was […]
Read MorePublished in Acta Anaesthesiol Scand. 2015 Apr;59(4):496-504 Authors: Telnes A et al BACKGROUND: Multiple studies suggest that transversus abdominis plane (TAP) block (without intrathecal morphine) after Caesarean section (CS) reduces post-operative morphine consumption. In our study, we wanted to compare the analgesic effect of TAP block with infiltration of the wound after CS. METHODS: We included […]
Read MoreAuthors: Mouncey PR et al., N Engl J Med 2015 Apr 2; 372:1301 A third trial shows no benefit for early goal-directed therapy for septic shock. In 2001, a single-center randomized trial demonstrated a significant mortality benefit for early goal-directed therapy (EGDT) in patients with septic shock (NEJM JW Gen Med Dec 15 2001 and N Engl J Med 2001; […]
Read MoreOpioid-induced hyperalgesia is among the most pressing concerns in the national discussion of opioid addiction, underscored by the US Food and Drug Administration’s (FDA) call for clinical trials to better understand the risks, but the issue is mired in more complexities and confusion than many may even realize, an expert says. Norman Harden, MD, from […]
Read MoreAuthors: Paul A van Beest et al BMC Anesthesiol. 2014;14(122) Background Tissue hypoperfusion occurs frequently during surgery and may contribute to postoperative organ dysfunction. There is a need for perioperative treatment protocols aiming at improving tissue oxygenation (StO2). We hypothesised that intra-operative optimisation of StO2 improves tissue perfusion and thus reduces postoperative complications. Furthermore, we evaluated the feasibility […]
Read MorePublished in Cochrane Database Syst Rev. 2015 Mar 29 Authors: Mkontwana N et al BACKGROUND: Oral analgesia is a convenient and widely used form of pain relief following caesarean section. It includes various medications used at different doses alone or in adjunction to other form of analgesia. OBJECTIVES: To determine the effectiveness, safety and cost-effectiveness of […]
Read MoreExtended-release liposomal bupivacaine provides no benefit over standard bupivacaine for pain control after total knee replacement (TKA), according to a study presented here at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). William C. Schroer, MD, DePaul Hospital, St. Louis, Missouri, and colleagues randomised 111 patients undergoing primary TKA to receive […]
Read MoreThe current gold standard for shoulder surgery pain management is a single-shot nerve block to reduce pain during and after surgery, which is still performed under general anaesthetic. Doctors had thought that this freezing, coupled with oral painkillers, would manage pain and keep patients comfortable for the first 24 to 48 hours after surgery. However, […]
Read MorePublished in Anesthesia & Analgesia: May 2015-Volume 120 Issue 5 page 1114-1129 Authors: Abdallah, Faraj W. MD et al BACKGROUND: Interscalene block (ISB) can provide pain relief after shoulder surgery, but a reliable quantification of its analgesic benefits is lacking. This meta-analysis examines the effect of single-shot ISB on analgesic outcomes during the first 48 […]
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