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Published in Paediatr Anaesth. 2015 May Authors: Sargin et al BACKGROUND: General anesthesia is often preferred for dental surgery or rehabilitation in developmentally delayed pediatric patients. Bispectral index monitoring is used to monitor the depth of anesthesia and to ensure early recovery. However, studies on the topic in developmentally delayed pediatric patients are limited. AIM: To evaluate […]
Read MorePublished in Paediatr Anaesth, 2015 May Authors: Chidambaran V et al BACKGROUND: Optimal dosing of propofol to maintain appropriate anesthetic depth is challenging in severely obese (SO) adolescents. We previously reported that total body weight (TBW) is predictive of propofol clearance. This study was aimed at characterizing pharmacokinetics (PK) and pharmacodynamics (PD) of propofol in SO […]
Read MoreAuthors: Goldberg H et al. JAMA 2015 May 19. And treatment offered no relief from pain. Oral steroids are used commonly in patients with acute lumbar radiculopathy or sciatica, but strong evidence of benefit is lacking. In this study, researchers at a large California health system randomized 269 patients (mean age, 46) with acute sciatica, magnetic resonance […]
Read MoreThe table below shows the top 100 diagnosis-related groups in the United States in 2013 based on total inpatient discharges. The Centers for Medicare and Medicaid services released the data Monday as part of a push to make the costs for these treatments more transparent. The data only includes treatments billed in a fee-for-service model […]
Read MorePerioperative β-blockade was associated with lower 30-day mortality in patients with three to four cardiac risk factors undergoing noncardiac surgery (NCS), but with increased mortality in patients with no cardiac risk factors, according to a retrospective cohort study published in May JAMA Surgery. “Perioperative β-blockade is widely accepted in patients who undergo cardiac surgery,” write Mark […]
Read MorePhysicians must become better prepared to answer patients’ questions about cannabis because its use in medicine is exploding, according to a leading researcher. “It’s high time we got up to speed with the language and the issues around communication on this,” said Mark Ware, MBBS, MSc, from McGill University Health Centre in Montreal, Quebec, Canada. […]
Read MoreChildren who underwent surgery with general anesthesia before 4 years of age later scored lower on tests for listening comprehension and performance IQ than children who did not undergo anesthesia, in a study for June Pediatrics has revealed. Although the researchers failed to find the kind of measurable neuronal deletion seen in animal studies of anesthesia […]
Read MoreAuthors: Marco G et al., Anesth Analg 2015 Jun 3; Increasing body-mass index, age, and propofol dose were predictors of swallowing impairment and aspiration in this single-center observational study. Deep sedation is becoming increasingly popular in a variety of clinical settings to facilitate medical and surgical procedures. Sedatives have the potential to affect swallowing function and protective […]
Read MoreAuthors: Campbell G et al; Pain Med, 2015 May 22 OBJECTIVE: There is increasing concern about the appropriateness of prescribing pharmaceutical opioids for chronic non-cancer pain (CNCP), given the risks of problematic use and dependence. This article examines pharmaceutical opioid dose and dependence and examines the correlates of each. DESIGN: Baseline data were obtained from a […]
Read MoreThe US Food and Drug Administration has approved fentanyl iontophoretic transdermal system (Ionsys, The Medicines Co), the first needle-free, patient-controlled, preprogrammed fentanyl delivery system for management of acute postoperative pain in adults requiring opioid analgesia in the hospital, according to a company news release. Ionsys is a “novel alternative” to traditional intravenous patient-controlled analgesia that uses […]
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