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Anesthesia & Analgesia: April 2015 Issue 1 page 149-158 Authors: Heesen, Michael MD et al BACKGROUND: Patient-controlled epidural analgesia (PCEA) has gained popularity, but it is still unclear whether adding a background infusion confers any benefit. METHODS: A systematic literature search in PubMed, Embase, CINAHL, LILACS, CENTRAL, Clinicaltrials.gov, and ISI WOS was performed to identify […]
Read MorePublished in Anesthesia & Analgesia: May 2015 Authors: Peralta, Feyce MD et al BACKGROUND: Unintentional dural puncture is a known risk after epidural or combined spinal-epidural procedures, occurring in approximately 1% of labor epidural catheters placed in parturients with normal body habitus but may be as high as 4% in morbidly obese parturients. Anecdotal experience […]
Read MorePublished in Anesthesia & Analgesia: April 2015 Authors: Fortier, Louis-Philippe MSc, MD, FRCPC et BACKGROUND: Postoperative residual neuromuscular blockade (NMB), defined as a train-of-four (TOF) ratio of <0.9, is an established risk factor for critical postoperative respiratory events and increased morbidity. At present, little is known about the occurrence of residual NMB in Canada. The […]
Read MoreA fast-acting transdermal gel using a proprietary formulation of the nonsteroidal anti-inflammatory drug (NSAID) ketoprofen (Topofen, Achelios Therapeutics) reduced pain severity in patients with severe migraine with and without aura compared with placebo and had few adverse effects. Results from a phase 2a trial of the gel were presented here at the American Academy of […]
Read MorePublished in Anesthesia & Analgesia May 2015 Authors: Weingarten, Toby N. MD et al BACKGROUND: The aim of this study was to identify patient and procedural characteristics associated with postoperative respiratory depression or sedation requiring naloxone intervention. METHODS: We identified patients who received naloxone to reverse opioid-induced respiratory depression or sedation within 48 hours after […]
Read MoreAnesthesia & Analgesia: May 2015 Authors: Perotti, Luciano MD et al BACKGROUND: Epidural infusion of levobupivacaine and ropivacaine provides adequate postoperative pain management by minimizing side effects related to IV opioids and improving patient outcome. The safety profile of different drugs can be better estimated by comparing their pharmacokinetic profiles than by considering their objective […]
Read MorePublished in Eur J Pediatr. 2015 May Authors: Sienkiewicz E. et al Abstract In paediatric patients, esophagogastroduodenoscopy (EGD) is commonly performed with the use of sedation. The aim of the study was to compare the effectiveness of propofol and midazolam in providing procedural amnesia and controlling behaviour in children undergoing diagnostic EGD. Children (9-16 years), classified to the […]
Read MoreThe use of femoral nerve block in the Emergency Room (ER) to help quell the pain caused by acute hip fracture is feasible in older adults, according to a study presented here at the 2015 Annual Scientific Meeting of the American Geriatrics Society (AGS). The development will help in early pain relief following a fall, […]
Read MorePublished in Anesthesia & Analgesia: May 2015 Authors: Short, Timothy G. MBChB, MD, FANZCA et al BACKGROUND: An association between relatively deep anesthesia, as guided by the bispectral index (BIS), and increased postoperative mortality has been demonstrated in 6 of 8 published observational studies, but association does not necessarily mean causality. Small clinical trials of […]
Read MoreVolume 12, Number 1 Carin A. Hagberg, MD Joseph C. Gabel Professor and Chair Department of Anesthesiology The University of Texas Medical School at Houston Director of Advanced Airway Management Memorial Hermann Hospital–Texas Medical Center Houston, Texas Executive Director 2009-Present, Society for Airway Management Management of the difficult airway remains one of the most relevant […]
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